Secretion of Recombinant Interleukin-22 by Engineered <named-content content-type="genus-species">Lactobacillus reuteri</named-content> Reduces Fatty Liver Disease in a Mouse Model of Diet-Induced Obesity

Secretion of Recombinant Interleukin-22 by Engineered <named-content content-type="genus-species">Lactobacillus reuteri</named-content> Reduces Fatty Liver Disease in a Mouse Model of Diet-Induced Obesity

ABSTRACT The incidence of metabolic syndrome continues to rise globally. In mice, intravenous administration of interleukin-22 (IL-22) ameliorates various disease phenotypes associated with diet-induced metabolic syndrome. In patients, oral treatment is favored over intravenous treatment, but method...

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Autores principales: Jee-Hwan Oh, Kathryn L. Schueler, Donnie S. Stapleton, Laura M. Alexander, Chi-Liang Eric Yen, Mark P. Keller, Alan D. Attie, Jan-Peter van Pijkeren
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
diet-induced metabolic syndrome
fatty liver disease
IL-22
Lactobacillus reuteri
probiotic
engineered probiotic
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/0f213e589b174cc3ad9814872f2e3b93
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