Sleeping sickness is a circadian disorder

African sleeping sickness is well known for the alterations of sleeping patterns, but it is not known how circadian biology is altered by the causative pathogen Trypanosoma brucei. Here the authors show T. brucei causes a disorder of the cellular circadian clock that is unrelated to the immune respo...

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Autores principales: Filipa Rijo-Ferreira, Tânia Carvalho, Cristina Afonso, Margarida Sanches-Vaz, Rui M Costa, Luísa M. Figueiredo, Joseph S. Takahashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0f231e1bd7a54c6bbcb5e406fef9da4a
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spelling oai:doaj.org-article:0f231e1bd7a54c6bbcb5e406fef9da4a2021-12-02T16:50:08ZSleeping sickness is a circadian disorder10.1038/s41467-017-02484-22041-1723https://doaj.org/article/0f231e1bd7a54c6bbcb5e406fef9da4a2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02484-2https://doaj.org/toc/2041-1723African sleeping sickness is well known for the alterations of sleeping patterns, but it is not known how circadian biology is altered by the causative pathogen Trypanosoma brucei. Here the authors show T. brucei causes a disorder of the cellular circadian clock that is unrelated to the immune response to the parasite.Filipa Rijo-FerreiraTânia CarvalhoCristina AfonsoMargarida Sanches-VazRui M CostaLuísa M. FigueiredoJoseph S. TakahashiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Filipa Rijo-Ferreira
Tânia Carvalho
Cristina Afonso
Margarida Sanches-Vaz
Rui M Costa
Luísa M. Figueiredo
Joseph S. Takahashi
Sleeping sickness is a circadian disorder
description African sleeping sickness is well known for the alterations of sleeping patterns, but it is not known how circadian biology is altered by the causative pathogen Trypanosoma brucei. Here the authors show T. brucei causes a disorder of the cellular circadian clock that is unrelated to the immune response to the parasite.
format article
author Filipa Rijo-Ferreira
Tânia Carvalho
Cristina Afonso
Margarida Sanches-Vaz
Rui M Costa
Luísa M. Figueiredo
Joseph S. Takahashi
author_facet Filipa Rijo-Ferreira
Tânia Carvalho
Cristina Afonso
Margarida Sanches-Vaz
Rui M Costa
Luísa M. Figueiredo
Joseph S. Takahashi
author_sort Filipa Rijo-Ferreira
title Sleeping sickness is a circadian disorder
title_short Sleeping sickness is a circadian disorder
title_full Sleeping sickness is a circadian disorder
title_fullStr Sleeping sickness is a circadian disorder
title_full_unstemmed Sleeping sickness is a circadian disorder
title_sort sleeping sickness is a circadian disorder
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0f231e1bd7a54c6bbcb5e406fef9da4a
work_keys_str_mv AT filiparijoferreira sleepingsicknessisacircadiandisorder
AT taniacarvalho sleepingsicknessisacircadiandisorder
AT cristinaafonso sleepingsicknessisacircadiandisorder
AT margaridasanchesvaz sleepingsicknessisacircadiandisorder
AT ruimcosta sleepingsicknessisacircadiandisorder
AT luisamfigueiredo sleepingsicknessisacircadiandisorder
AT josephstakahashi sleepingsicknessisacircadiandisorder
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