Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling

Mass spectrometry-based quantitative proteomics aim to identify and quantify proteins from complex biological samples. Here, the authors developed a method for simultaneous high-throughput protein labelling and on-demand matrix removal within nanoseconds.

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Autores principales: Gongyu Li, Fengfei Ma, Qinjingwen Cao, Zhen Zheng, Kellen DeLaney, Rui Liu, Lingjun Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/0f2343e010814fb68dde9d6e1076df75
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spelling oai:doaj.org-article:0f2343e010814fb68dde9d6e1076df752021-12-02T15:36:01ZNanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling10.1038/s41467-019-12548-02041-1723https://doaj.org/article/0f2343e010814fb68dde9d6e1076df752019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12548-0https://doaj.org/toc/2041-1723Mass spectrometry-based quantitative proteomics aim to identify and quantify proteins from complex biological samples. Here, the authors developed a method for simultaneous high-throughput protein labelling and on-demand matrix removal within nanoseconds.Gongyu LiFengfei MaQinjingwen CaoZhen ZhengKellen DeLaneyRui LiuLingjun LiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gongyu Li
Fengfei Ma
Qinjingwen Cao
Zhen Zheng
Kellen DeLaney
Rui Liu
Lingjun Li
Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
description Mass spectrometry-based quantitative proteomics aim to identify and quantify proteins from complex biological samples. Here, the authors developed a method for simultaneous high-throughput protein labelling and on-demand matrix removal within nanoseconds.
format article
author Gongyu Li
Fengfei Ma
Qinjingwen Cao
Zhen Zheng
Kellen DeLaney
Rui Liu
Lingjun Li
author_facet Gongyu Li
Fengfei Ma
Qinjingwen Cao
Zhen Zheng
Kellen DeLaney
Rui Liu
Lingjun Li
author_sort Gongyu Li
title Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
title_short Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
title_full Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
title_fullStr Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
title_full_unstemmed Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
title_sort nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/0f2343e010814fb68dde9d6e1076df75
work_keys_str_mv AT gongyuli nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
AT fengfeima nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
AT qinjingwencao nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
AT zhenzheng nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
AT kellendelaney nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
AT ruiliu nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
AT lingjunli nanosecondphotochemicallypromotedclickchemistryforenhancedneuropeptidevisualizationandrapidproteinlabeling
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