Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene
The structures of amyloid fibres are currently primarily studied through solid state NMR and cryo-EM. Here the authors present a free-standing graphene support device that allows diffraction imaging of non-crystalline amyloid fibrils with single X-ray pulses from an X-ray free-electron laser.
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Nature Portfolio
2018
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oai:doaj.org-article:0f29de3d658a4701815f6d96e5366ab42021-12-02T15:34:26ZFemtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene10.1038/s41467-018-04116-92041-1723https://doaj.org/article/0f29de3d658a4701815f6d96e5366ab42018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04116-9https://doaj.org/toc/2041-1723The structures of amyloid fibres are currently primarily studied through solid state NMR and cryo-EM. Here the authors present a free-standing graphene support device that allows diffraction imaging of non-crystalline amyloid fibrils with single X-ray pulses from an X-ray free-electron laser.Carolin SeuringKartik AyyerEleftheria FilippakiMiriam BarthelmessJean-Nicolas LongchampPhilippe RinglerTommaso PardiniDavid H. WojtasMatthew A. ColemanKaterina DörnerSilje FuglerudGreger HammarinBirgit HabensteinAnnette E. LangkildeAntoine LoquetAlke MeentsRoland RiekHenning StahlbergSébastien BoutetMark S. HunterJason KoglinMengning LiangHelen M. GinnRick P. MillaneMatthias FrankAnton BartyHenry N. ChapmanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Carolin Seuring Kartik Ayyer Eleftheria Filippaki Miriam Barthelmess Jean-Nicolas Longchamp Philippe Ringler Tommaso Pardini David H. Wojtas Matthew A. Coleman Katerina Dörner Silje Fuglerud Greger Hammarin Birgit Habenstein Annette E. Langkilde Antoine Loquet Alke Meents Roland Riek Henning Stahlberg Sébastien Boutet Mark S. Hunter Jason Koglin Mengning Liang Helen M. Ginn Rick P. Millane Matthias Frank Anton Barty Henry N. Chapman Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| description |
The structures of amyloid fibres are currently primarily studied through solid state NMR and cryo-EM. Here the authors present a free-standing graphene support device that allows diffraction imaging of non-crystalline amyloid fibrils with single X-ray pulses from an X-ray free-electron laser. |
| format |
article |
| author |
Carolin Seuring Kartik Ayyer Eleftheria Filippaki Miriam Barthelmess Jean-Nicolas Longchamp Philippe Ringler Tommaso Pardini David H. Wojtas Matthew A. Coleman Katerina Dörner Silje Fuglerud Greger Hammarin Birgit Habenstein Annette E. Langkilde Antoine Loquet Alke Meents Roland Riek Henning Stahlberg Sébastien Boutet Mark S. Hunter Jason Koglin Mengning Liang Helen M. Ginn Rick P. Millane Matthias Frank Anton Barty Henry N. Chapman |
| author_facet |
Carolin Seuring Kartik Ayyer Eleftheria Filippaki Miriam Barthelmess Jean-Nicolas Longchamp Philippe Ringler Tommaso Pardini David H. Wojtas Matthew A. Coleman Katerina Dörner Silje Fuglerud Greger Hammarin Birgit Habenstein Annette E. Langkilde Antoine Loquet Alke Meents Roland Riek Henning Stahlberg Sébastien Boutet Mark S. Hunter Jason Koglin Mengning Liang Helen M. Ginn Rick P. Millane Matthias Frank Anton Barty Henry N. Chapman |
| author_sort |
Carolin Seuring |
| title |
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| title_short |
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| title_full |
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| title_fullStr |
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| title_full_unstemmed |
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| title_sort |
femtosecond x-ray coherent diffraction of aligned amyloid fibrils on low background graphene |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/0f29de3d658a4701815f6d96e5366ab4 |
| work_keys_str_mv |
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| _version_ |
1718386821649399808 |