Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae.

In response to severe environmental stresses eukaryotic cells shut down translation and accumulate components of the translational machinery in stress granules (SGs). Since they contain mainly mRNA, translation initiation factors and 40S ribosomal subunits, they have been referred to as dominant acc...

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Autores principales: Tomas Grousl, Pavel Ivanov, Ivana Malcova, Petr Pompach, Ivana Frydlova, Renata Slaba, Lenka Senohrabkova, Lenka Novakova, Jiri Hasek
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/0f2cda6a202840abbdbebc51beb35bc6
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