Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study

Abstract Body stuffers routinely receive conservative treatment, i.e. administration of the laxative polyethylene glycol for the passage of ingested drug baggies and observation. Endoscopic baggie removal may offer a safe alternative that could result in shorter hospitalization. We aimed to compare...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mahtab Shabani, Marzieh Kefayati, Hossein Hassanian-Moghaddam, Nasim Zamani, Rebecca McDonald
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/0f333647eb0f43c1a3fd268e90542d85
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:0f333647eb0f43c1a3fd268e90542d85
record_format dspace
spelling oai:doaj.org-article:0f333647eb0f43c1a3fd268e90542d852021-12-02T11:37:22ZComplications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study10.1038/s41598-021-84898-z2045-2322https://doaj.org/article/0f333647eb0f43c1a3fd268e90542d852021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84898-zhttps://doaj.org/toc/2045-2322Abstract Body stuffers routinely receive conservative treatment, i.e. administration of the laxative polyethylene glycol for the passage of ingested drug baggies and observation. Endoscopic baggie removal may offer a safe alternative that could result in shorter hospitalization. We aimed to compare complications, hospital stay, and final outcome in body stuffers assigned to endoscopy versus conservative treatment. This is an observational prospective study of body stuffers presenting to a clinical toxicology center in Tehran (Iran) in 2016–2019, irrespective of the drug ingested. Eligible patients had baggies in their upper gastrointestinal tract and presented without severe poisoning. Patients received either endoscopy or conservative treatment, and clinical outcomes were compared between the groups. A total of 69 patients were enrolled, with a median age of 29 years (range 18–64), among whom 1 was female (2%). Eighteen and 51 patients were endoscopically and conservatively managed, respectively. Drugs most commonly ingested were heroin in endoscopy patients (8/18 cases; 44%) and methamphetamine in the conservative group (28/51 cases; 55%). Endoscopy patients had a shorter hospital stay (median 1.5 vs. 2 days, P = 0.018). In the conservative group, one patient died, and the rate of complications was significantly higher, with more patients experiencing side effects (OR = 1.4, 95% CI = 1.2, 1.7) and requiring intubation (OR = 1.3, 95% CI = 1.1, 1.5). Endoscopic retrieval was associated with fewer complications and shorter hospitalization. Endoscopy may be a safe treatment for body stuffers without severe poisoning on presentation.Mahtab ShabaniMarzieh KefayatiHossein Hassanian-MoghaddamNasim ZamaniRebecca McDonaldNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Mahtab Shabani
Marzieh Kefayati
Hossein Hassanian-Moghaddam
Nasim Zamani
Rebecca McDonald
Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
description Abstract Body stuffers routinely receive conservative treatment, i.e. administration of the laxative polyethylene glycol for the passage of ingested drug baggies and observation. Endoscopic baggie removal may offer a safe alternative that could result in shorter hospitalization. We aimed to compare complications, hospital stay, and final outcome in body stuffers assigned to endoscopy versus conservative treatment. This is an observational prospective study of body stuffers presenting to a clinical toxicology center in Tehran (Iran) in 2016–2019, irrespective of the drug ingested. Eligible patients had baggies in their upper gastrointestinal tract and presented without severe poisoning. Patients received either endoscopy or conservative treatment, and clinical outcomes were compared between the groups. A total of 69 patients were enrolled, with a median age of 29 years (range 18–64), among whom 1 was female (2%). Eighteen and 51 patients were endoscopically and conservatively managed, respectively. Drugs most commonly ingested were heroin in endoscopy patients (8/18 cases; 44%) and methamphetamine in the conservative group (28/51 cases; 55%). Endoscopy patients had a shorter hospital stay (median 1.5 vs. 2 days, P = 0.018). In the conservative group, one patient died, and the rate of complications was significantly higher, with more patients experiencing side effects (OR = 1.4, 95% CI = 1.2, 1.7) and requiring intubation (OR = 1.3, 95% CI = 1.1, 1.5). Endoscopic retrieval was associated with fewer complications and shorter hospitalization. Endoscopy may be a safe treatment for body stuffers without severe poisoning on presentation.
format article
author Mahtab Shabani
Marzieh Kefayati
Hossein Hassanian-Moghaddam
Nasim Zamani
Rebecca McDonald
author_facet Mahtab Shabani
Marzieh Kefayati
Hossein Hassanian-Moghaddam
Nasim Zamani
Rebecca McDonald
author_sort Mahtab Shabani
title Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
title_short Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
title_full Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
title_fullStr Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
title_full_unstemmed Complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
title_sort complications and hospital stay after endoscopic retrieval of drug baggies in body stuffers: an observational prospective study
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0f333647eb0f43c1a3fd268e90542d85
work_keys_str_mv AT mahtabshabani complicationsandhospitalstayafterendoscopicretrievalofdrugbaggiesinbodystuffersanobservationalprospectivestudy
AT marziehkefayati complicationsandhospitalstayafterendoscopicretrievalofdrugbaggiesinbodystuffersanobservationalprospectivestudy
AT hosseinhassanianmoghaddam complicationsandhospitalstayafterendoscopicretrievalofdrugbaggiesinbodystuffersanobservationalprospectivestudy
AT nasimzamani complicationsandhospitalstayafterendoscopicretrievalofdrugbaggiesinbodystuffersanobservationalprospectivestudy
AT rebeccamcdonald complicationsandhospitalstayafterendoscopicretrievalofdrugbaggiesinbodystuffersanobservationalprospectivestudy
_version_ 1718395744355876864