Peficitinib improves bone fragility by recovering bone turnover imbalance in arthritic mice
Peficitinib, a pan-JAK inhibitor, is known to suppress the activation of fibroblast-like synoviocytes (FLSs) and thereby reduces joint inflammation associated with rheumatoid arthritis (RA). However, the effect on osteoporosis in RA remains to be elucidated. In this study, the effect of peficitinib...
Guardado en:
Autores principales: | Shingo Sugahara, Kaori Hanaoka, Takashi Emori, Nobuaki Takeshita, Yasutomo Fujii, Masaki Nakano, Takako Suzuki, Jun Takahashi, Yukio Nakamura |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://doaj.org/article/0f3811cf2f52458db0d2eb57ee8a9f18 |
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