UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae

Coenzyme Q (CoQ) is a lipid made in the inner mitochondrial membrane with antioxidant roles throughout the cell, but regulation of its cellular distribution is unclear. Here the authors identify two proteins that have reciprocal CoQ trafficking functions to help coordinate CoQ localization in yeast.

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Autores principales: Zachary A. Kemmerer, Kyle P. Robinson, Jonathan M. Schmitz, Mateusz Manicki, Brett R. Paulson, Adam Jochem, Paul D. Hutchins, Joshua J. Coon, David J. Pagliarini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0f3ed6133c854d93a8edf70a6550d460
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spelling oai:doaj.org-article:0f3ed6133c854d93a8edf70a6550d4602021-12-02T14:53:37ZUbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae10.1038/s41467-021-25084-72041-1723https://doaj.org/article/0f3ed6133c854d93a8edf70a6550d4602021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25084-7https://doaj.org/toc/2041-1723Coenzyme Q (CoQ) is a lipid made in the inner mitochondrial membrane with antioxidant roles throughout the cell, but regulation of its cellular distribution is unclear. Here the authors identify two proteins that have reciprocal CoQ trafficking functions to help coordinate CoQ localization in yeast.Zachary A. KemmererKyle P. RobinsonJonathan M. SchmitzMateusz ManickiBrett R. PaulsonAdam JochemPaul D. HutchinsJoshua J. CoonDavid J. PagliariniNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zachary A. Kemmerer
Kyle P. Robinson
Jonathan M. Schmitz
Mateusz Manicki
Brett R. Paulson
Adam Jochem
Paul D. Hutchins
Joshua J. Coon
David J. Pagliarini
UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
description Coenzyme Q (CoQ) is a lipid made in the inner mitochondrial membrane with antioxidant roles throughout the cell, but regulation of its cellular distribution is unclear. Here the authors identify two proteins that have reciprocal CoQ trafficking functions to help coordinate CoQ localization in yeast.
format article
author Zachary A. Kemmerer
Kyle P. Robinson
Jonathan M. Schmitz
Mateusz Manicki
Brett R. Paulson
Adam Jochem
Paul D. Hutchins
Joshua J. Coon
David J. Pagliarini
author_facet Zachary A. Kemmerer
Kyle P. Robinson
Jonathan M. Schmitz
Mateusz Manicki
Brett R. Paulson
Adam Jochem
Paul D. Hutchins
Joshua J. Coon
David J. Pagliarini
author_sort Zachary A. Kemmerer
title UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
title_short UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
title_full UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
title_fullStr UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
title_full_unstemmed UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
title_sort ubib proteins regulate cellular coq distribution in saccharomyces cerevisiae
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0f3ed6133c854d93a8edf70a6550d460
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AT mateuszmanicki ubibproteinsregulatecellularcoqdistributioninsaccharomycescerevisiae
AT brettrpaulson ubibproteinsregulatecellularcoqdistributioninsaccharomycescerevisiae
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AT davidjpagliarini ubibproteinsregulatecellularcoqdistributioninsaccharomycescerevisiae
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