The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II

The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II

The response to DNA damage-stalled RNA polymerase II leads to the assembly of the transcription-coupled repair (TCR) complex on actively transcribed strands. Here, the authors reveal the complex assembly mechanism of the TCR complex in human cells.

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Detalles Bibliográficos
Autores principales: Yana van der Weegen, Hadar Golan-Berman, Tycho E. T. Mevissen, Katja Apelt, Román González-Prieto, Joachim Goedhart, Elisheva E. Heilbrun, Alfred C. O. Vertegaal, Diana van den Heuvel, Johannes C. Walter, Sheera Adar, Martijn S. Luijsterburg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
Q
Acceso en línea:https://doaj.org/article/0f49222ee301497fadd3b4e75734a6d9
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Sumario:The response to DNA damage-stalled RNA polymerase II leads to the assembly of the transcription-coupled repair (TCR) complex on actively transcribed strands. Here, the authors reveal the complex assembly mechanism of the TCR complex in human cells.

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