Neutralizing antibody titres in SARS-CoV-2 infections

Here, the authors perform plaque reduction neutralization (PRNT) assays quantitating SARS-CoV-2 specific neutralizing antibodies from 195 patients in different disease states and find that patients with severe disease exhibit higher peaks of neutralizing antibody titres than patients with mild or as...

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Autores principales:	Eric H. Y. Lau, Owen T. Y. Tsang, David S. C. Hui, Mike Y. W. Kwan, Wai-hung Chan, Susan S. Chiu, Ronald L. W. Ko, Kin H. Chan, Samuel M. S. Cheng, Ranawaka A. P. M. Perera, Benjamin J. Cowling, Leo L. M. Poon, Malik Peiris
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0f559f41752a4dab8ef7684e7c8625f7
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spelling	oai:doaj.org-article:0f559f41752a4dab8ef7684e7c8625f72021-12-02T15:16:22ZNeutralizing antibody titres in SARS-CoV-2 infections10.1038/s41467-020-20247-42041-1723https://doaj.org/article/0f559f41752a4dab8ef7684e7c8625f72021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20247-4https://doaj.org/toc/2041-1723Here, the authors perform plaque reduction neutralization (PRNT) assays quantitating SARS-CoV-2 specific neutralizing antibodies from 195 patients in different disease states and find that patients with severe disease exhibit higher peaks of neutralizing antibody titres than patients with mild or asymptomatic infections and that serum neutralizing antibody persists for over 6 months in most people.Eric H. Y. LauOwen T. Y. TsangDavid S. C. HuiMike Y. W. KwanWai-hung ChanSusan S. ChiuRonald L. W. KoKin H. ChanSamuel M. S. ChengRanawaka A. P. M. PereraBenjamin J. CowlingLeo L. M. PoonMalik PeirisNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eric H. Y. Lau Owen T. Y. Tsang David S. C. Hui Mike Y. W. Kwan Wai-hung Chan Susan S. Chiu Ronald L. W. Ko Kin H. Chan Samuel M. S. Cheng Ranawaka A. P. M. Perera Benjamin J. Cowling Leo L. M. Poon Malik Peiris Neutralizing antibody titres in SARS-CoV-2 infections
description	Here, the authors perform plaque reduction neutralization (PRNT) assays quantitating SARS-CoV-2 specific neutralizing antibodies from 195 patients in different disease states and find that patients with severe disease exhibit higher peaks of neutralizing antibody titres than patients with mild or asymptomatic infections and that serum neutralizing antibody persists for over 6 months in most people.
format	article
author	Eric H. Y. Lau Owen T. Y. Tsang David S. C. Hui Mike Y. W. Kwan Wai-hung Chan Susan S. Chiu Ronald L. W. Ko Kin H. Chan Samuel M. S. Cheng Ranawaka A. P. M. Perera Benjamin J. Cowling Leo L. M. Poon Malik Peiris
author_facet	Eric H. Y. Lau Owen T. Y. Tsang David S. C. Hui Mike Y. W. Kwan Wai-hung Chan Susan S. Chiu Ronald L. W. Ko Kin H. Chan Samuel M. S. Cheng Ranawaka A. P. M. Perera Benjamin J. Cowling Leo L. M. Poon Malik Peiris
author_sort	Eric H. Y. Lau
title	Neutralizing antibody titres in SARS-CoV-2 infections
title_short	Neutralizing antibody titres in SARS-CoV-2 infections
title_full	Neutralizing antibody titres in SARS-CoV-2 infections
title_fullStr	Neutralizing antibody titres in SARS-CoV-2 infections
title_full_unstemmed	Neutralizing antibody titres in SARS-CoV-2 infections
title_sort	neutralizing antibody titres in sars-cov-2 infections
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0f559f41752a4dab8ef7684e7c8625f7
work_keys_str_mv	AT erichylau neutralizingantibodytitresinsarscov2infections AT owentytsang neutralizingantibodytitresinsarscov2infections AT davidschui neutralizingantibodytitresinsarscov2infections AT mikeywkwan neutralizingantibodytitresinsarscov2infections AT waihungchan neutralizingantibodytitresinsarscov2infections AT susanschiu neutralizingantibodytitresinsarscov2infections AT ronaldlwko neutralizingantibodytitresinsarscov2infections AT kinhchan neutralizingantibodytitresinsarscov2infections AT samuelmscheng neutralizingantibodytitresinsarscov2infections AT ranawakaapmperera neutralizingantibodytitresinsarscov2infections AT benjaminjcowling neutralizingantibodytitresinsarscov2infections AT leolmpoon neutralizingantibodytitresinsarscov2infections AT malikpeiris neutralizingantibodytitresinsarscov2infections
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Neutralizing antibody titres in SARS-CoV-2 infections

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