Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants

Ubiquitylation of H2B is associated with transcription and regulation of chromatin structure. Here, the authors perform an unbiased screen to identify the role of chromatin modifications on ubiquitylation of H2BK120 and characterize the crosstalk between H2BK120ub and H2A modifications and variants.

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Autores principales: Felix Wojcik, Geoffrey P. Dann, Leslie Y. Beh, Galia T. Debelouchina, Raphael Hofmann, Tom W. Muir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0f57f5223d79484f8c00e20c85b246c0
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spelling oai:doaj.org-article:0f57f5223d79484f8c00e20c85b246c02021-12-02T14:39:48ZFunctional crosstalk between histone H2B ubiquitylation and H2A modifications and variants10.1038/s41467-018-03895-52041-1723https://doaj.org/article/0f57f5223d79484f8c00e20c85b246c02018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03895-5https://doaj.org/toc/2041-1723Ubiquitylation of H2B is associated with transcription and regulation of chromatin structure. Here, the authors perform an unbiased screen to identify the role of chromatin modifications on ubiquitylation of H2BK120 and characterize the crosstalk between H2BK120ub and H2A modifications and variants.Felix WojcikGeoffrey P. DannLeslie Y. BehGalia T. DebelouchinaRaphael HofmannTom W. MuirNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Felix Wojcik
Geoffrey P. Dann
Leslie Y. Beh
Galia T. Debelouchina
Raphael Hofmann
Tom W. Muir
Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
description Ubiquitylation of H2B is associated with transcription and regulation of chromatin structure. Here, the authors perform an unbiased screen to identify the role of chromatin modifications on ubiquitylation of H2BK120 and characterize the crosstalk between H2BK120ub and H2A modifications and variants.
format article
author Felix Wojcik
Geoffrey P. Dann
Leslie Y. Beh
Galia T. Debelouchina
Raphael Hofmann
Tom W. Muir
author_facet Felix Wojcik
Geoffrey P. Dann
Leslie Y. Beh
Galia T. Debelouchina
Raphael Hofmann
Tom W. Muir
author_sort Felix Wojcik
title Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
title_short Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
title_full Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
title_fullStr Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
title_full_unstemmed Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants
title_sort functional crosstalk between histone h2b ubiquitylation and h2a modifications and variants
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0f57f5223d79484f8c00e20c85b246c0
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