A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo

A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo

In vivo decorporation of U(VI) from bones is an unsolved challenge because of the formation of stable uranium phosphate complexes. Here, the authors develop a hydroxypyridonone-based ligand with strong uranium complexation and low cytotoxicity. They find this ligand effectively removes uranium from...

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Autores principales: Xiaomei Wang, Xing Dai, Cen Shi, Jianmei Wan, Mark A. Silver, Linjuan Zhang, Lanhua Chen, Xuan Yi, Bizheng Chen, Duo Zhang, Kai Yang, Juan Diwu, Jianqiang Wang, Yujie Xu, Ruhong Zhou, Zhifang Chai, Shuao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/0f5f19fdfda140a9b8a4128474a4e8c7
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https://doaj.org/article/0f5f19fdfda140a9b8a4128474a4e8c7

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