Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform

Kevin Ziyang Chng et al. develop a microfluidic platform using a fluorescence quenching approach to assess transient changes in oxygen release rate of single red blood cells. They observe that biologically older red blood cells have a faster O2 release rate than younger cells and that storage of blo...

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Autores principales: Kevin Ziyang Chng, Yan Cheng Ng, Bumseok Namgung, Justin Kok Soon Tan, Soyeon Park, Sim Leng Tien, Hwa Liang Leo, Sangho Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0f5f2bf1d86641dabf78ebccd07594e7
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Sumario:Kevin Ziyang Chng et al. develop a microfluidic platform using a fluorescence quenching approach to assess transient changes in oxygen release rate of single red blood cells. They observe that biologically older red blood cells have a faster O2 release rate than younger cells and that storage of blood enhances this release rate.