Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform

Kevin Ziyang Chng et al. develop a microfluidic platform using a fluorescence quenching approach to assess transient changes in oxygen release rate of single red blood cells. They observe that biologically older red blood cells have a faster O2 release rate than younger cells and that storage of blo...

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Autores principales: Kevin Ziyang Chng, Yan Cheng Ng, Bumseok Namgung, Justin Kok Soon Tan, Soyeon Park, Sim Leng Tien, Hwa Liang Leo, Sangho Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0f5f2bf1d86641dabf78ebccd07594e7
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spelling oai:doaj.org-article:0f5f2bf1d86641dabf78ebccd07594e72021-12-02T15:52:46ZAssessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform10.1038/s42003-021-01793-z2399-3642https://doaj.org/article/0f5f2bf1d86641dabf78ebccd07594e72021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01793-zhttps://doaj.org/toc/2399-3642Kevin Ziyang Chng et al. develop a microfluidic platform using a fluorescence quenching approach to assess transient changes in oxygen release rate of single red blood cells. They observe that biologically older red blood cells have a faster O2 release rate than younger cells and that storage of blood enhances this release rate.Kevin Ziyang ChngYan Cheng NgBumseok NamgungJustin Kok Soon TanSoyeon ParkSim Leng TienHwa Liang LeoSangho KimNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Kevin Ziyang Chng
Yan Cheng Ng
Bumseok Namgung
Justin Kok Soon Tan
Soyeon Park
Sim Leng Tien
Hwa Liang Leo
Sangho Kim
Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
description Kevin Ziyang Chng et al. develop a microfluidic platform using a fluorescence quenching approach to assess transient changes in oxygen release rate of single red blood cells. They observe that biologically older red blood cells have a faster O2 release rate than younger cells and that storage of blood enhances this release rate.
format article
author Kevin Ziyang Chng
Yan Cheng Ng
Bumseok Namgung
Justin Kok Soon Tan
Soyeon Park
Sim Leng Tien
Hwa Liang Leo
Sangho Kim
author_facet Kevin Ziyang Chng
Yan Cheng Ng
Bumseok Namgung
Justin Kok Soon Tan
Soyeon Park
Sim Leng Tien
Hwa Liang Leo
Sangho Kim
author_sort Kevin Ziyang Chng
title Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
title_short Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
title_full Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
title_fullStr Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
title_full_unstemmed Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
title_sort assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0f5f2bf1d86641dabf78ebccd07594e7
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