TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
Changes in ECM are of predictive value in pancreatic and colorectal cancer prognosis. Here, the authors perform a pan-cancer analysis and find a subset of ECM genes that is linked to TGF-β signalling signature and is correlated with immunotherapy failure.
Guardado en:
Autores principales: | Ankur Chakravarthy, Lubaba Khan, Nathan Peter Bensler, Pinaki Bose, Daniel D. De Carvalho |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/0f6644ecb6fb477fb4de336f46f9241d |
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