The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates

Abstract The aim of this study was to investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and pancreatic steatosis (PS) in patients with biopsy-proven NAFLD. 228 patients with biopsy-proven NAFLD patients who admitted to the Faculty of Medicine of Demiroglu Bilim University...

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Autores principales:	Bedriye Koyuncu Sokmen, Tolga Sahin, Alihan Oral, Erdem Kocak, Nagihan Inan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0f6b2b6044184c8894ca4fb7452c890d
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spelling	oai:doaj.org-article:0f6b2b6044184c8894ca4fb7452c890d2021-12-02T15:53:46ZThe comparison of pancreatic and hepatic steatosis in healthy liver donor candidates10.1038/s41598-021-83871-02045-2322https://doaj.org/article/0f6b2b6044184c8894ca4fb7452c890d2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83871-0https://doaj.org/toc/2045-2322Abstract The aim of this study was to investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and pancreatic steatosis (PS) in patients with biopsy-proven NAFLD. 228 patients with biopsy-proven NAFLD patients who admitted to the Faculty of Medicine of Demiroglu Bilim University between 2004 and 2019 were included in the study. Demographic, laboratory, histological and radiological findings of the patients were recorded retrospectively. Hepatosteatosis (HS) levels were measured by both CT and biopsy, while PS levels were measured by 3 different CT-based techniques. 89 (39%) of the patients were female and 139 (61%) were male. The mean body mass index (BMI) was 27.2 ± 4.0. Biochemical parameters were within normal limits. Liver biopsy showed a significant correlation with HS grade on CT scan (p < 0.001). When CT findings were compared, a significant correlation was found between PS and HS (p < 0.05), but there was no correlation between the HS level in biopsy and the pancreatic adiposity on CT (p > 0.05). Our study was the first to compare biopsy-proven NAFLD and PS, and no correlation was found between biopsy-proven NAFLD and PS.Bedriye Koyuncu SokmenTolga SahinAlihan OralErdem KocakNagihan InanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Bedriye Koyuncu Sokmen Tolga Sahin Alihan Oral Erdem Kocak Nagihan Inan The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
description	Abstract The aim of this study was to investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and pancreatic steatosis (PS) in patients with biopsy-proven NAFLD. 228 patients with biopsy-proven NAFLD patients who admitted to the Faculty of Medicine of Demiroglu Bilim University between 2004 and 2019 were included in the study. Demographic, laboratory, histological and radiological findings of the patients were recorded retrospectively. Hepatosteatosis (HS) levels were measured by both CT and biopsy, while PS levels were measured by 3 different CT-based techniques. 89 (39%) of the patients were female and 139 (61%) were male. The mean body mass index (BMI) was 27.2 ± 4.0. Biochemical parameters were within normal limits. Liver biopsy showed a significant correlation with HS grade on CT scan (p < 0.001). When CT findings were compared, a significant correlation was found between PS and HS (p < 0.05), but there was no correlation between the HS level in biopsy and the pancreatic adiposity on CT (p > 0.05). Our study was the first to compare biopsy-proven NAFLD and PS, and no correlation was found between biopsy-proven NAFLD and PS.
format	article
author	Bedriye Koyuncu Sokmen Tolga Sahin Alihan Oral Erdem Kocak Nagihan Inan
author_facet	Bedriye Koyuncu Sokmen Tolga Sahin Alihan Oral Erdem Kocak Nagihan Inan
author_sort	Bedriye Koyuncu Sokmen
title	The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
title_short	The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
title_full	The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
title_fullStr	The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
title_full_unstemmed	The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
title_sort	comparison of pancreatic and hepatic steatosis in healthy liver donor candidates
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0f6b2b6044184c8894ca4fb7452c890d
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The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates

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