Single-Shot Local Injection of Microfragmented Fat Tissue Loaded with Paclitaxel Induces Potent Growth Inhibition of Hepatocellular Carcinoma in Nude Mice

Hepatocellular carcinoma (HCC) is poorly beneficiated by intravenous chemotherapy due to inadequate availability of drugs at the tumor site. We previously demonstrated that human micro-fragmented adipose tissue (MFAT) and its devitalized counterpart (DMFAT) could be effective natural scaffolds to de...

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Autores principales:	Giulio Alessandri, Augusto Pessina, Rita Paroni, Luisa Bercich, Francesca Paino, Michele Dei Cas, Moris Cadei, Arnaldo Caruso, Marco Schiariti, Francesco Restelli, Offer Zeira, Carlo Tremolada, Nazario Portolani
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	paclitaxel micro-fragmented fat tissue hepatocarcinoma drug delivery natural scaffold Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/0f6baa87087a4237828c5129b3285387
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Single-Shot Local Injection of Microfragmented Fat Tissue Loaded with Paclitaxel Induces Potent Growth Inhibition of Hepatocellular Carcinoma in Nude Mice

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