Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.

Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.

The ecotropic virus integration site 1 (EVI1) transcription factor is associated with human myeloid malignancy of poor prognosis and is overexpressed in 8-10% of adult AML and strikingly up to 27% of pediatric MLL-rearranged leukemias. For the first time, we report comprehensive genomewide EVI1 bind...

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Autores principales: Carolyn Glass, Charles Wuertzer, Xiaohui Cui, Yingtao Bi, Ramana Davuluri, Ying-Yi Xiao, Michael Wilson, Kristina Owens, Yi Zhang, Archibald Perkins
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/0f6e454064b94a89990b99d6229fd382
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