Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems

Abstract The International Federation of Gynecology and Obstetrics (FIGO) cervical cancer staging system was modified in 2018, introducing new stage IB subdivisions and new lymph node status considerations in stage IIIC. We compared cervical cancer survival outcomes according to the 2014 and 2018 FI...

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Autores principales:	Wonkyo Shin, Tae Young Ham, Young Ran Park, Myong Cheol Lim, Young-Joo Won
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0f6ebcc88cd9454b9a2ea201d7fbd149
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spelling	oai:doaj.org-article:0f6ebcc88cd9454b9a2ea201d7fbd1492021-12-02T11:45:03ZComparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems10.1038/s41598-021-86283-22045-2322https://doaj.org/article/0f6ebcc88cd9454b9a2ea201d7fbd1492021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86283-2https://doaj.org/toc/2045-2322Abstract The International Federation of Gynecology and Obstetrics (FIGO) cervical cancer staging system was modified in 2018, introducing new stage IB subdivisions and new lymph node status considerations in stage IIIC. We compared cervical cancer survival outcomes according to the 2014 and 2018 FIGO staging systems. We selected 10% of cervical cancer cases (2010–2015) from the Korean national cancer registry (2010–2015) through a systematic sampling method. We collected information using a collaborative stage data collection system and evaluated the results according to both staging systems. The log-rank test was used to analyze overall survival differences. No significant difference in survival was observed between 2018 subdivisions IB1/IB2/IB3 (P = 0.069), whereas a considerable difference was observed between these subdivisions according to histological subtypes. In the 2018 FIGO staging system, stage IIIC had better survival than stage IIIA/IIIB (P < 0.001). We observed considerable heterogeneity in 2018 stage IIIC related to the corresponding stages of the 2014 staging system (stages IA1–IIIB). The size of the primary cervical mass was related to survival (P < 0.001). In conclusion, using lymph node status to define stage IIIC captured a broad range of prognoses. The inclusion of primary tumor size considerations may improve the staging accuracy of advanced cervical cancer.Wonkyo ShinTae Young HamYoung Ran ParkMyong Cheol LimYoung-Joo WonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Wonkyo Shin Tae Young Ham Young Ran Park Myong Cheol Lim Young-Joo Won Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems
description	Abstract The International Federation of Gynecology and Obstetrics (FIGO) cervical cancer staging system was modified in 2018, introducing new stage IB subdivisions and new lymph node status considerations in stage IIIC. We compared cervical cancer survival outcomes according to the 2014 and 2018 FIGO staging systems. We selected 10% of cervical cancer cases (2010–2015) from the Korean national cancer registry (2010–2015) through a systematic sampling method. We collected information using a collaborative stage data collection system and evaluated the results according to both staging systems. The log-rank test was used to analyze overall survival differences. No significant difference in survival was observed between 2018 subdivisions IB1/IB2/IB3 (P = 0.069), whereas a considerable difference was observed between these subdivisions according to histological subtypes. In the 2018 FIGO staging system, stage IIIC had better survival than stage IIIA/IIIB (P < 0.001). We observed considerable heterogeneity in 2018 stage IIIC related to the corresponding stages of the 2014 staging system (stages IA1–IIIB). The size of the primary cervical mass was related to survival (P < 0.001). In conclusion, using lymph node status to define stage IIIC captured a broad range of prognoses. The inclusion of primary tumor size considerations may improve the staging accuracy of advanced cervical cancer.
format	article
author	Wonkyo Shin Tae Young Ham Young Ran Park Myong Cheol Lim Young-Joo Won
author_facet	Wonkyo Shin Tae Young Ham Young Ran Park Myong Cheol Lim Young-Joo Won
author_sort	Wonkyo Shin
title	Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems
title_short	Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems
title_full	Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems
title_fullStr	Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems
title_full_unstemmed	Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems
title_sort	comparing survival outcomes for cervical cancer based on the 2014 and 2018 international federation of gynecology and obstetrics staging systems
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0f6ebcc88cd9454b9a2ea201d7fbd149
work_keys_str_mv	AT wonkyoshin comparingsurvivaloutcomesforcervicalcancerbasedonthe2014and2018internationalfederationofgynecologyandobstetricsstagingsystems AT taeyoungham comparingsurvivaloutcomesforcervicalcancerbasedonthe2014and2018internationalfederationofgynecologyandobstetricsstagingsystems AT youngranpark comparingsurvivaloutcomesforcervicalcancerbasedonthe2014and2018internationalfederationofgynecologyandobstetricsstagingsystems AT myongcheollim comparingsurvivaloutcomesforcervicalcancerbasedonthe2014and2018internationalfederationofgynecologyandobstetricsstagingsystems AT youngjoowon comparingsurvivaloutcomesforcervicalcancerbasedonthe2014and2018internationalfederationofgynecologyandobstetricsstagingsystems
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Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems

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