Topology and structure of an engineered human cohesin complex bound to Pds5B

Cohesin is a ring-shaped protein complex that structures chromatin and mediates sister chromatid cohesion. Here the authors rigidify cohesin using engineered Smc1 and Smc3 and generated 3D models showing how Pds5B forms an integral part of the cohesin ring.

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Autores principales:	Michael T. Hons, Pim J. Huis in ‘t Veld, Jan Kaesler, Pascaline Rombaut, Alexander Schleiffer, Franz Herzog, Holger Stark, Jan-Michael Peters
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0f7233fdcb064b2d901ef3b4d2d7f3bf
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spelling	oai:doaj.org-article:0f7233fdcb064b2d901ef3b4d2d7f3bf2021-12-02T17:32:38ZTopology and structure of an engineered human cohesin complex bound to Pds5B10.1038/ncomms125232041-1723https://doaj.org/article/0f7233fdcb064b2d901ef3b4d2d7f3bf2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12523https://doaj.org/toc/2041-1723Cohesin is a ring-shaped protein complex that structures chromatin and mediates sister chromatid cohesion. Here the authors rigidify cohesin using engineered Smc1 and Smc3 and generated 3D models showing how Pds5B forms an integral part of the cohesin ring.Michael T. HonsPim J. Huis in ‘t VeldJan KaeslerPascaline RombautAlexander SchleifferFranz HerzogHolger StarkJan-Michael PetersNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael T. Hons Pim J. Huis in ‘t Veld Jan Kaesler Pascaline Rombaut Alexander Schleiffer Franz Herzog Holger Stark Jan-Michael Peters Topology and structure of an engineered human cohesin complex bound to Pds5B
description	Cohesin is a ring-shaped protein complex that structures chromatin and mediates sister chromatid cohesion. Here the authors rigidify cohesin using engineered Smc1 and Smc3 and generated 3D models showing how Pds5B forms an integral part of the cohesin ring.
format	article
author	Michael T. Hons Pim J. Huis in ‘t Veld Jan Kaesler Pascaline Rombaut Alexander Schleiffer Franz Herzog Holger Stark Jan-Michael Peters
author_facet	Michael T. Hons Pim J. Huis in ‘t Veld Jan Kaesler Pascaline Rombaut Alexander Schleiffer Franz Herzog Holger Stark Jan-Michael Peters
author_sort	Michael T. Hons
title	Topology and structure of an engineered human cohesin complex bound to Pds5B
title_short	Topology and structure of an engineered human cohesin complex bound to Pds5B
title_full	Topology and structure of an engineered human cohesin complex bound to Pds5B
title_fullStr	Topology and structure of an engineered human cohesin complex bound to Pds5B
title_full_unstemmed	Topology and structure of an engineered human cohesin complex bound to Pds5B
title_sort	topology and structure of an engineered human cohesin complex bound to pds5b
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0f7233fdcb064b2d901ef3b4d2d7f3bf
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Topology and structure of an engineered human cohesin complex bound to Pds5B

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