Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients

Mohammed K El Mallah1, Molly M Walsh2, Sandra S Stinnett2, Sanjay G Asrani21Ocala Eye, Ocala, Florida, USA; 2Duke University Eye Center, Durham, North Carolina, USAPurpose: To evaluate the effect of selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients.Patients and methods:...

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Autores principales:	Mohammed K El Mallah, Molly M Walsh, Sandra S Stinnett, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/0f7f08a821834a66834b43f42c62e893
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spelling	oai:doaj.org-article:0f7f08a821834a66834b43f42c62e8932021-12-02T06:23:29ZSelective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients1177-54671177-5483https://doaj.org/article/0f7f08a821834a66834b43f42c62e8932010-07-01T00:00:00Zhttp://www.dovepress.com/selective-laser-trabeculoplasty-reduces-mean-iop-and-iop-variation-in--a4954https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mohammed K El Mallah1, Molly M Walsh2, Sandra S Stinnett2, Sanjay G Asrani21Ocala Eye, Ocala, Florida, USA; 2Duke University Eye Center, Durham, North Carolina, USAPurpose: To evaluate the effect of selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients.Patients and methods: A retrospective review was performed of NTG patients who had undergone SLT at the Duke University Eye Center between 12/2002 and 7/2005. For each eye of each patient at pre-laser and post-laser time points, the IOP measurements were summarized by mean, standard deviation, and range. Then for each of these descriptive statistics, the differences between pre-laser and post-laser values were obtained. Statistical analysis was performed using a random effects model. Main outcome measures: difference in mean IOP, standard deviation of IOP, and range of IOP.Results: Thirty-one eyes of 18 patients were included for analysis. The average of the mean &shy;pre-operative IOP measurements was 14.3 &plusmn; 2.6 mmHg compared to 12.2 &plusmn; 1.7 mmHg (P &lt; 0.001) post-operatively. The mean pre-operative standard deviation was 1.9 &plusmn; 0.9 mmHg compared to 1.0 &plusmn; 0.6 mmHg (P = 0.002) post-operatively while the mean IOP range prior to treatment was 4.5 &plusmn; 2.5 mmHg compared to 2.5 &plusmn; 1.9 mmHg (P = 0.017) after treatment.Conclusion: In this pilot study, SLT was found to lower mean IOP and intervisit IOP &shy;variation in NTG patients. Given the importance of IOP variation and its association with glaucoma &shy;progression, measurement of IOP variation following treatment with SLT may be considered.Keywords: SLT, NTG, laser, glaucoma Mohammed K El MallahMolly M WalshSandra S Stinnettet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 889-893 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Mohammed K El Mallah Molly M Walsh Sandra S Stinnett et al Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
description	Mohammed K El Mallah1, Molly M Walsh2, Sandra S Stinnett2, Sanjay G Asrani21Ocala Eye, Ocala, Florida, USA; 2Duke University Eye Center, Durham, North Carolina, USAPurpose: To evaluate the effect of selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients.Patients and methods: A retrospective review was performed of NTG patients who had undergone SLT at the Duke University Eye Center between 12/2002 and 7/2005. For each eye of each patient at pre-laser and post-laser time points, the IOP measurements were summarized by mean, standard deviation, and range. Then for each of these descriptive statistics, the differences between pre-laser and post-laser values were obtained. Statistical analysis was performed using a random effects model. Main outcome measures: difference in mean IOP, standard deviation of IOP, and range of IOP.Results: Thirty-one eyes of 18 patients were included for analysis. The average of the mean &shy;pre-operative IOP measurements was 14.3 &plusmn; 2.6 mmHg compared to 12.2 &plusmn; 1.7 mmHg (P &lt; 0.001) post-operatively. The mean pre-operative standard deviation was 1.9 &plusmn; 0.9 mmHg compared to 1.0 &plusmn; 0.6 mmHg (P = 0.002) post-operatively while the mean IOP range prior to treatment was 4.5 &plusmn; 2.5 mmHg compared to 2.5 &plusmn; 1.9 mmHg (P = 0.017) after treatment.Conclusion: In this pilot study, SLT was found to lower mean IOP and intervisit IOP &shy;variation in NTG patients. Given the importance of IOP variation and its association with glaucoma &shy;progression, measurement of IOP variation following treatment with SLT may be considered.Keywords: SLT, NTG, laser, glaucoma
format	article
author	Mohammed K El Mallah Molly M Walsh Sandra S Stinnett et al
author_facet	Mohammed K El Mallah Molly M Walsh Sandra S Stinnett et al
author_sort	Mohammed K El Mallah
title	Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
title_short	Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
title_full	Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
title_fullStr	Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
title_full_unstemmed	Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients
title_sort	selective laser trabeculoplasty reduces mean iop and iop variation in normal tension glaucoma patients
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/0f7f08a821834a66834b43f42c62e893
work_keys_str_mv	AT mohammedkelmallah selectivelasertrabeculoplastyreducesmeaniopandiopvariationinnormaltensionglaucomapatients AT mollymwalsh selectivelasertrabeculoplastyreducesmeaniopandiopvariationinnormaltensionglaucomapatients AT sandrasstinnett selectivelasertrabeculoplastyreducesmeaniopandiopvariationinnormaltensionglaucomapatients AT etal selectivelasertrabeculoplastyreducesmeaniopandiopvariationinnormaltensionglaucomapatients
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Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients

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