Timed daily exercise remodels circadian rhythms in mice

Using mice with disrupted neuropeptide signaling, Hughes et al. show that daily scheduled voluntary exercise (SVE) promotes suprachiasmatic nuclei (SCN) clock cell synchrony and robust 24 h rhythms in behavior. This study suggests the potential utility of regular exercise as a non-invasive intervent...

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Autores principales:	Alun Thomas Lloyd Hughes, Rayna Eve Samuels, Beatriz Baño-Otálora, Mino David Charles Belle, Sven Wegner, Clare Guilding, Rebecca Catrin Northeast, Andrew Stewart Irvine Loudon, John Gigg, Hugh David Piggins
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0f7f59e65316410d88152cdba79bd9cc
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spelling	oai:doaj.org-article:0f7f59e65316410d88152cdba79bd9cc2021-12-02T17:41:06ZTimed daily exercise remodels circadian rhythms in mice10.1038/s42003-021-02239-22399-3642https://doaj.org/article/0f7f59e65316410d88152cdba79bd9cc2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02239-2https://doaj.org/toc/2399-3642Using mice with disrupted neuropeptide signaling, Hughes et al. show that daily scheduled voluntary exercise (SVE) promotes suprachiasmatic nuclei (SCN) clock cell synchrony and robust 24 h rhythms in behavior. This study suggests the potential utility of regular exercise as a non-invasive intervention for the elderly or mentally ill, where circadian rhythms can be poorly aligned to the external world.Alun Thomas Lloyd HughesRayna Eve SamuelsBeatriz Baño-OtáloraMino David Charles BelleSven WegnerClare GuildingRebecca Catrin NortheastAndrew Stewart Irvine LoudonJohn GiggHugh David PigginsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Alun Thomas Lloyd Hughes Rayna Eve Samuels Beatriz Baño-Otálora Mino David Charles Belle Sven Wegner Clare Guilding Rebecca Catrin Northeast Andrew Stewart Irvine Loudon John Gigg Hugh David Piggins Timed daily exercise remodels circadian rhythms in mice
description	Using mice with disrupted neuropeptide signaling, Hughes et al. show that daily scheduled voluntary exercise (SVE) promotes suprachiasmatic nuclei (SCN) clock cell synchrony and robust 24 h rhythms in behavior. This study suggests the potential utility of regular exercise as a non-invasive intervention for the elderly or mentally ill, where circadian rhythms can be poorly aligned to the external world.
format	article
author	Alun Thomas Lloyd Hughes Rayna Eve Samuels Beatriz Baño-Otálora Mino David Charles Belle Sven Wegner Clare Guilding Rebecca Catrin Northeast Andrew Stewart Irvine Loudon John Gigg Hugh David Piggins
author_facet	Alun Thomas Lloyd Hughes Rayna Eve Samuels Beatriz Baño-Otálora Mino David Charles Belle Sven Wegner Clare Guilding Rebecca Catrin Northeast Andrew Stewart Irvine Loudon John Gigg Hugh David Piggins
author_sort	Alun Thomas Lloyd Hughes
title	Timed daily exercise remodels circadian rhythms in mice
title_short	Timed daily exercise remodels circadian rhythms in mice
title_full	Timed daily exercise remodels circadian rhythms in mice
title_fullStr	Timed daily exercise remodels circadian rhythms in mice
title_full_unstemmed	Timed daily exercise remodels circadian rhythms in mice
title_sort	timed daily exercise remodels circadian rhythms in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0f7f59e65316410d88152cdba79bd9cc
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Timed daily exercise remodels circadian rhythms in mice

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