Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study

Jiaqiang Wang,1 Shuping Dong,1 Jianpo Zhang,2 Shilei Gao,1 Zhehuang Li,1 Po Li,1 Junhui Yuan,3 Zhichao Tian1 1Department of Bone and Soft Tissue, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of China; 2Patholog...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wang J, Dong S, Zhang J, Gao S, Li Z, Li P, Yuan J, Tian Z
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	undifferentiated pleomorphic sarcoma neoplastic fever fever of unknown origin sarcoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/0f876bed58734a4882caa8e8117bb931
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0f876bed58734a4882caa8e8117bb931
record_format	dspace
spelling	oai:doaj.org-article:0f876bed58734a4882caa8e8117bb9312021-11-11T18:22:26ZUndifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study1179-1322https://doaj.org/article/0f876bed58734a4882caa8e8117bb9312021-11-01T00:00:00Zhttps://www.dovepress.com/undifferentiated-pleomorphic-sarcoma-with-neoplastic-fever-a-retrospec-peer-reviewed-fulltext-article-CMARhttps://doaj.org/toc/1179-1322Jiaqiang Wang,1 Shuping Dong,1 Jianpo Zhang,2 Shilei Gao,1 Zhehuang Li,1 Po Li,1 Junhui Yuan,3 Zhichao Tian1 1Department of Bone and Soft Tissue, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of China; 2Pathology Department, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of China; 3Medical Imaging Department, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of ChinaCorrespondence: Zhichao TianDepartment of Bone and Soft Tissue, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Dongming Road, Zhengzhou, Henan Province, 450008, People’s Republic of ChinaTel +86-13592413731Fax +86-371-65961505Email tianzhichaoyy@163.comBackground: Although the annual incidence of undifferentiated pleomorphic sarcoma (UPS) is extremely low, it can be subdivided into different subtypes. UPS with fever of unknown origin (also known as neoplastic fever) is a specific subtype of UPS, which shows certain clinical features that differentiate it from other UPS subtypes. However, no studies have focused on this rare UPS subtype. This study retrospectively analyzed the clinical data of patients with UPS to provide a reference for the diagnosis and treatment of UPS with neoplastic fever.Methods: This study included patients with UPS who were diagnosed and treated between June 2012 and June 2018. We examined whether these patients had a history of neoplastic fever. The characteristics of patients with UPS with neoplastic fever were summarized and analyzed.Results: We reviewed the medical records of 183 patients with UPS. Seven (3.83%) of these patients had neoplastic fever. In patients with UPS with neoplastic fever, the primary lesions were located in the extremities and across the muscle space. In these patients, magnetic resonance imaging showed necrosis within the tumor body and extensive soft tissue edema around the tumor body. Patients with UPS with neoplastic fever had a lower metastasis rate (14.29% vs 44.94%) and a higher 3-year survival rate (85.71% vs 59.55%) than those without neoplastic fever.Conclusion: UPS with neoplastic fever is characterized by intratumoral necrosis and extensive edema of the surrounding soft tissues. Patients with UPS with neoplastic fever may have a better prognosis than those without neoplastic fever.Keywords: undifferentiated pleomorphic sarcoma, neoplastic fever, fever of unknown origin, sarcomaWang JDong SZhang JGao SLi ZLi PYuan JTian ZDove Medical Pressarticleundifferentiated pleomorphic sarcomaneoplastic feverfever of unknown originsarcomaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancer Management and Research, Vol Volume 13, Pp 8481-8487 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	undifferentiated pleomorphic sarcoma neoplastic fever fever of unknown origin sarcoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	undifferentiated pleomorphic sarcoma neoplastic fever fever of unknown origin sarcoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Wang J Dong S Zhang J Gao S Li Z Li P Yuan J Tian Z Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study
description	Jiaqiang Wang,1 Shuping Dong,1 Jianpo Zhang,2 Shilei Gao,1 Zhehuang Li,1 Po Li,1 Junhui Yuan,3 Zhichao Tian1 1Department of Bone and Soft Tissue, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of China; 2Pathology Department, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of China; 3Medical Imaging Department, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan Province, 450008, People’s Republic of ChinaCorrespondence: Zhichao TianDepartment of Bone and Soft Tissue, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Dongming Road, Zhengzhou, Henan Province, 450008, People’s Republic of ChinaTel +86-13592413731Fax +86-371-65961505Email tianzhichaoyy@163.comBackground: Although the annual incidence of undifferentiated pleomorphic sarcoma (UPS) is extremely low, it can be subdivided into different subtypes. UPS with fever of unknown origin (also known as neoplastic fever) is a specific subtype of UPS, which shows certain clinical features that differentiate it from other UPS subtypes. However, no studies have focused on this rare UPS subtype. This study retrospectively analyzed the clinical data of patients with UPS to provide a reference for the diagnosis and treatment of UPS with neoplastic fever.Methods: This study included patients with UPS who were diagnosed and treated between June 2012 and June 2018. We examined whether these patients had a history of neoplastic fever. The characteristics of patients with UPS with neoplastic fever were summarized and analyzed.Results: We reviewed the medical records of 183 patients with UPS. Seven (3.83%) of these patients had neoplastic fever. In patients with UPS with neoplastic fever, the primary lesions were located in the extremities and across the muscle space. In these patients, magnetic resonance imaging showed necrosis within the tumor body and extensive soft tissue edema around the tumor body. Patients with UPS with neoplastic fever had a lower metastasis rate (14.29% vs 44.94%) and a higher 3-year survival rate (85.71% vs 59.55%) than those without neoplastic fever.Conclusion: UPS with neoplastic fever is characterized by intratumoral necrosis and extensive edema of the surrounding soft tissues. Patients with UPS with neoplastic fever may have a better prognosis than those without neoplastic fever.Keywords: undifferentiated pleomorphic sarcoma, neoplastic fever, fever of unknown origin, sarcoma
format	article
author	Wang J Dong S Zhang J Gao S Li Z Li P Yuan J Tian Z
author_facet	Wang J Dong S Zhang J Gao S Li Z Li P Yuan J Tian Z
author_sort	Wang J
title	Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study
title_short	Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study
title_full	Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study
title_fullStr	Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study
title_full_unstemmed	Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study
title_sort	undifferentiated pleomorphic sarcoma with neoplastic fever: a retrospective study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/0f876bed58734a4882caa8e8117bb931
work_keys_str_mv	AT wangj undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT dongs undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT zhangj undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT gaos undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT liz undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT lip undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT yuanj undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy AT tianz undifferentiatedpleomorphicsarcomawithneoplasticfeveraretrospectivestudy
_version_	1718431805802020864

Undifferentiated Pleomorphic Sarcoma with Neoplastic Fever: A Retrospective Study

Ejemplares similares