Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ

Multiple whole-genome alignment is a challenging problem in bioinformatics, especially when computational resources are limited. Here the authors present SibeliaZ, an algorithm and software based on analysis of de Bruijn graphs, which provides improved computational efficiency and scalability.

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Detalles Bibliográficos
Autores principales:	Ilia Minkin, Paul Medvedev
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0f88c82844904b66bfae58b980448170
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spelling	oai:doaj.org-article:0f88c82844904b66bfae58b9804481702021-12-02T13:57:55ZScalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ10.1038/s41467-020-19777-82041-1723https://doaj.org/article/0f88c82844904b66bfae58b9804481702020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19777-8https://doaj.org/toc/2041-1723Multiple whole-genome alignment is a challenging problem in bioinformatics, especially when computational resources are limited. Here the authors present SibeliaZ, an algorithm and software based on analysis of de Bruijn graphs, which provides improved computational efficiency and scalability.Ilia MinkinPaul MedvedevNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ilia Minkin Paul Medvedev Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ
description	Multiple whole-genome alignment is a challenging problem in bioinformatics, especially when computational resources are limited. Here the authors present SibeliaZ, an algorithm and software based on analysis of de Bruijn graphs, which provides improved computational efficiency and scalability.
format	article
author	Ilia Minkin Paul Medvedev
author_facet	Ilia Minkin Paul Medvedev
author_sort	Ilia Minkin
title	Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ
title_short	Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ
title_full	Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ
title_fullStr	Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ
title_full_unstemmed	Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ
title_sort	scalable multiple whole-genome alignment and locally collinear block construction with sibeliaz
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0f88c82844904b66bfae58b980448170
work_keys_str_mv	AT iliaminkin scalablemultiplewholegenomealignmentandlocallycollinearblockconstructionwithsibeliaz AT paulmedvedev scalablemultiplewholegenomealignmentandlocallycollinearblockconstructionwithsibeliaz
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Scalable multiple whole-genome alignment and locally collinear block construction with SibeliaZ

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