Prediction of antibacterial activity from physicochemical properties of antimicrobial peptides.

Consensus is gathering that antimicrobial peptides that exert their antibacterial action at the membrane level must reach a local concentration threshold to become active. Studies of peptide interaction with model membranes do identify such disruptive thresholds but demonstrations of the possible co...

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Autores principales: Manuel N Melo, Rafael Ferre, Lídia Feliu, Eduard Bardají, Marta Planas, Miguel A R B Castanho
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/0f8e4ca8a8844d4fb81a53878382ccfe
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