ESR1 amplification in breast cancer by optimized RNase FISH: frequent but low-level and heterogeneous.
Prevalence of ESR1 amplification in breast cancer is highly disputed and discrepancies have been related to different technical protocols and different scoring approaches. In addition, pre-mRNA artifacts have been proposed to influence outcome of ESR1 FISH analysis. We analyzed ESR1 gene copy number...
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Autores principales: | Cathy B Moelans, Frederik Holst, Olaf Hellwinkel, Ronald Simon, Paul J van Diest |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/0f96661f173f4429996bf67558021dab |
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