A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features
By examining Latin American individuals of mixed European, Native American and African ancestry, Adhikari et al. identify novel loci influencing various features of facial and scalp hair. The study also provides experimental evidence that one of the implicated genes (PRSS53) is expressed in the hair...
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Nature Portfolio
2016
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oai:doaj.org-article:0f97fbb66079458f805844b2d61b335e2021-12-02T14:38:35ZA genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features10.1038/ncomms108152041-1723https://doaj.org/article/0f97fbb66079458f805844b2d61b335e2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10815https://doaj.org/toc/2041-1723By examining Latin American individuals of mixed European, Native American and African ancestry, Adhikari et al. identify novel loci influencing various features of facial and scalp hair. The study also provides experimental evidence that one of the implicated genes (PRSS53) is expressed in the hair follicle and that the top associated variant alters processing of this enzyme.Kaustubh AdhikariTania FontanilSantiago CalJavier Mendoza-RevillaMacarena Fuentes-GuajardoJuan-Camilo Chacón-DuqueFarah Al-SaadiJeanette A. JohanssonMirsha Quinto-SanchezVictor Acuña-AlonzoClaudia JaramilloWilliam AriasRodrigo Barquera LozanoGastón Macín PérezJorge Gómez-ValdésHugo Villamil-RamírezTábita HunemeierVirginia RamalloCaio C. Silva de CerqueiraMalena HurtadoValeria VillegasVanessa GranjaCarla GalloGiovanni PolettiLavinia Schuler-FacciniFrancisco M. SalzanoMaria-Cátira BortoliniSamuel Canizales-QuinterosFrancisco RothhammerGabriel BedoyaRolando Gonzalez-JoséDenis HeadonCarlos López-OtínDesmond J. TobinDavid BaldingAndrés Ruiz-LinaresNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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DOAJ |
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EN |
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Science Q |
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Science Q Kaustubh Adhikari Tania Fontanil Santiago Cal Javier Mendoza-Revilla Macarena Fuentes-Guajardo Juan-Camilo Chacón-Duque Farah Al-Saadi Jeanette A. Johansson Mirsha Quinto-Sanchez Victor Acuña-Alonzo Claudia Jaramillo William Arias Rodrigo Barquera Lozano Gastón Macín Pérez Jorge Gómez-Valdés Hugo Villamil-Ramírez Tábita Hunemeier Virginia Ramallo Caio C. Silva de Cerqueira Malena Hurtado Valeria Villegas Vanessa Granja Carla Gallo Giovanni Poletti Lavinia Schuler-Faccini Francisco M. Salzano Maria-Cátira Bortolini Samuel Canizales-Quinteros Francisco Rothhammer Gabriel Bedoya Rolando Gonzalez-José Denis Headon Carlos López-Otín Desmond J. Tobin David Balding Andrés Ruiz-Linares A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features |
| description |
By examining Latin American individuals of mixed European, Native American and African ancestry, Adhikari et al. identify novel loci influencing various features of facial and scalp hair. The study also provides experimental evidence that one of the implicated genes (PRSS53) is expressed in the hair follicle and that the top associated variant alters processing of this enzyme. |
| format |
article |
| author |
Kaustubh Adhikari Tania Fontanil Santiago Cal Javier Mendoza-Revilla Macarena Fuentes-Guajardo Juan-Camilo Chacón-Duque Farah Al-Saadi Jeanette A. Johansson Mirsha Quinto-Sanchez Victor Acuña-Alonzo Claudia Jaramillo William Arias Rodrigo Barquera Lozano Gastón Macín Pérez Jorge Gómez-Valdés Hugo Villamil-Ramírez Tábita Hunemeier Virginia Ramallo Caio C. Silva de Cerqueira Malena Hurtado Valeria Villegas Vanessa Granja Carla Gallo Giovanni Poletti Lavinia Schuler-Faccini Francisco M. Salzano Maria-Cátira Bortolini Samuel Canizales-Quinteros Francisco Rothhammer Gabriel Bedoya Rolando Gonzalez-José Denis Headon Carlos López-Otín Desmond J. Tobin David Balding Andrés Ruiz-Linares |
| author_facet |
Kaustubh Adhikari Tania Fontanil Santiago Cal Javier Mendoza-Revilla Macarena Fuentes-Guajardo Juan-Camilo Chacón-Duque Farah Al-Saadi Jeanette A. Johansson Mirsha Quinto-Sanchez Victor Acuña-Alonzo Claudia Jaramillo William Arias Rodrigo Barquera Lozano Gastón Macín Pérez Jorge Gómez-Valdés Hugo Villamil-Ramírez Tábita Hunemeier Virginia Ramallo Caio C. Silva de Cerqueira Malena Hurtado Valeria Villegas Vanessa Granja Carla Gallo Giovanni Poletti Lavinia Schuler-Faccini Francisco M. Salzano Maria-Cátira Bortolini Samuel Canizales-Quinteros Francisco Rothhammer Gabriel Bedoya Rolando Gonzalez-José Denis Headon Carlos López-Otín Desmond J. Tobin David Balding Andrés Ruiz-Linares |
| author_sort |
Kaustubh Adhikari |
| title |
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features |
| title_short |
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features |
| title_full |
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features |
| title_fullStr |
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features |
| title_full_unstemmed |
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features |
| title_sort |
genome-wide association scan in admixed latin americans identifies loci influencing facial and scalp hair features |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/0f97fbb66079458f805844b2d61b335e |
| work_keys_str_mv |
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