Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity

The role of the oral microbiome and its effect on dental diseases is gaining interest. Therefore, it has been sought to decrease the bacterial load to fight oral cavity diseases. In this study, composite materials based on chitosan, chitosan crosslinked with glutaraldehyde, chitosan with zinc oxide...

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Autores principales:	Candy del Carmen Gamboa-Solana, Martha Gabriela Chuc-Gamboa, Fernando Javier Aguilar-Pérez, Juan Valerio Cauich-Rodríguez, Rossana Faride Vargas-Coronado, David Alejandro Aguilar-Pérez, José Rubén Herrera-Atoche, Neith Pacheco
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	chitosan glutaraldehyde zinc oxide copper nanoparticles <i>S. aureus</i> <i>S. typhimurium</i> Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/0fa342a98e4d4603a0525727ce5f6b9f
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spelling	oai:doaj.org-article:0fa342a98e4d4603a0525727ce5f6b9f2021-11-25T18:47:42ZZinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity10.3390/polym132238612073-4360https://doaj.org/article/0fa342a98e4d4603a0525727ce5f6b9f2021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4360/13/22/3861https://doaj.org/toc/2073-4360The role of the oral microbiome and its effect on dental diseases is gaining interest. Therefore, it has been sought to decrease the bacterial load to fight oral cavity diseases. In this study, composite materials based on chitosan, chitosan crosslinked with glutaraldehyde, chitosan with zinc oxide particles, and chitosan with copper nanoparticles were prepared in the form of thin films, to evaluate a new alternative with a more significant impact on the oral cavity bacteria. The chemical structures and physical properties of the films were characterized using by Fourier transform infrared spectroscopy (FTIR,) Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), elemental analysis (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), scanning electron microscopy (SEM), and contact angle measurements. Subsequently, the antimicrobial activity of each material was evaluated by agar diffusion tests. No differences were found in the hydrophilicity of the films with the incorporation of ZnO or copper particles. Antimicrobial activity was found against <i>S. aureus</i> in the chitosan film crosslinked with glutaraldehyde, but not in the other compositions. In contrast antimicrobial activity against <i>S. typhimurium</i> was found in all films. Based on the data of present investigation, chitosan composite films could be an option for the control of microorganisms with potential applications in various fields, such as medical and food industry.Candy del Carmen Gamboa-SolanaMartha Gabriela Chuc-GamboaFernando Javier Aguilar-PérezJuan Valerio Cauich-RodríguezRossana Faride Vargas-CoronadoDavid Alejandro Aguilar-PérezJosé Rubén Herrera-AtocheNeith PachecoMDPI AGarticlechitosanglutaraldehydezinc oxidecopper nanoparticles<i>S. aureus</i><i>S. typhimurium</i>Organic chemistryQD241-441ENPolymers, Vol 13, Iss 3861, p 3861 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chitosan glutaraldehyde zinc oxide copper nanoparticles <i>S. aureus</i> <i>S. typhimurium</i> Organic chemistry QD241-441
spellingShingle	chitosan glutaraldehyde zinc oxide copper nanoparticles <i>S. aureus</i> <i>S. typhimurium</i> Organic chemistry QD241-441 Candy del Carmen Gamboa-Solana Martha Gabriela Chuc-Gamboa Fernando Javier Aguilar-Pérez Juan Valerio Cauich-Rodríguez Rossana Faride Vargas-Coronado David Alejandro Aguilar-Pérez José Rubén Herrera-Atoche Neith Pacheco Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
description	The role of the oral microbiome and its effect on dental diseases is gaining interest. Therefore, it has been sought to decrease the bacterial load to fight oral cavity diseases. In this study, composite materials based on chitosan, chitosan crosslinked with glutaraldehyde, chitosan with zinc oxide particles, and chitosan with copper nanoparticles were prepared in the form of thin films, to evaluate a new alternative with a more significant impact on the oral cavity bacteria. The chemical structures and physical properties of the films were characterized using by Fourier transform infrared spectroscopy (FTIR,) Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), elemental analysis (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), scanning electron microscopy (SEM), and contact angle measurements. Subsequently, the antimicrobial activity of each material was evaluated by agar diffusion tests. No differences were found in the hydrophilicity of the films with the incorporation of ZnO or copper particles. Antimicrobial activity was found against <i>S. aureus</i> in the chitosan film crosslinked with glutaraldehyde, but not in the other compositions. In contrast antimicrobial activity against <i>S. typhimurium</i> was found in all films. Based on the data of present investigation, chitosan composite films could be an option for the control of microorganisms with potential applications in various fields, such as medical and food industry.
format	article
author	Candy del Carmen Gamboa-Solana Martha Gabriela Chuc-Gamboa Fernando Javier Aguilar-Pérez Juan Valerio Cauich-Rodríguez Rossana Faride Vargas-Coronado David Alejandro Aguilar-Pérez José Rubén Herrera-Atoche Neith Pacheco
author_facet	Candy del Carmen Gamboa-Solana Martha Gabriela Chuc-Gamboa Fernando Javier Aguilar-Pérez Juan Valerio Cauich-Rodríguez Rossana Faride Vargas-Coronado David Alejandro Aguilar-Pérez José Rubén Herrera-Atoche Neith Pacheco
author_sort	Candy del Carmen Gamboa-Solana
title	Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
title_short	Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
title_full	Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
title_fullStr	Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
title_full_unstemmed	Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
title_sort	zinc oxide and copper chitosan composite films with antimicrobial activity
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/0fa342a98e4d4603a0525727ce5f6b9f
work_keys_str_mv	AT candydelcarmengamboasolana zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT marthagabrielachucgamboa zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT fernandojavieraguilarperez zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT juanvaleriocauichrodriguez zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT rossanafaridevargascoronado zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT davidalejandroaguilarperez zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT joserubenherreraatoche zincoxideandcopperchitosancompositefilmswithantimicrobialactivity AT neithpacheco zincoxideandcopperchitosancompositefilmswithantimicrobialactivity
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Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity

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