Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication

Histone mimicry of viral components is a strategy to subvert host factors for virus replication. Here, the authors show that an acetylated histone-like motif of the small Hepatitis Delta Antigen (S-HDAg) interacts with the chromatin remodeler BAZ2B to recruit the DNA-dependent RNA polymerase II for...

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Autores principales:	Natali Abeywickrama-Samarakoon, Jean-Claude Cortay, Camille Sureau, Susanne Müller, Dulce Alfaiate, Francesca Guerrieri, Apirat Chaikuad, Martin Schröder, Philippe Merle, Massimo Levrero, Paul Dény
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0fa57c165bda4e6aa2ee90cc3d885e92
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spelling	oai:doaj.org-article:0fa57c165bda4e6aa2ee90cc3d885e922021-12-02T14:41:13ZHepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication10.1038/s41467-020-14299-92041-1723https://doaj.org/article/0fa57c165bda4e6aa2ee90cc3d885e922020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14299-9https://doaj.org/toc/2041-1723Histone mimicry of viral components is a strategy to subvert host factors for virus replication. Here, the authors show that an acetylated histone-like motif of the small Hepatitis Delta Antigen (S-HDAg) interacts with the chromatin remodeler BAZ2B to recruit the DNA-dependent RNA polymerase II for HDV RNA replication.Natali Abeywickrama-SamarakoonJean-Claude CortayCamille SureauSusanne MüllerDulce AlfaiateFrancesca GuerrieriApirat ChaikuadMartin SchröderPhilippe MerleMassimo LevreroPaul DényNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Natali Abeywickrama-Samarakoon Jean-Claude Cortay Camille Sureau Susanne Müller Dulce Alfaiate Francesca Guerrieri Apirat Chaikuad Martin Schröder Philippe Merle Massimo Levrero Paul Dény Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
description	Histone mimicry of viral components is a strategy to subvert host factors for virus replication. Here, the authors show that an acetylated histone-like motif of the small Hepatitis Delta Antigen (S-HDAg) interacts with the chromatin remodeler BAZ2B to recruit the DNA-dependent RNA polymerase II for HDV RNA replication.
format	article
author	Natali Abeywickrama-Samarakoon Jean-Claude Cortay Camille Sureau Susanne Müller Dulce Alfaiate Francesca Guerrieri Apirat Chaikuad Martin Schröder Philippe Merle Massimo Levrero Paul Dény
author_facet	Natali Abeywickrama-Samarakoon Jean-Claude Cortay Camille Sureau Susanne Müller Dulce Alfaiate Francesca Guerrieri Apirat Chaikuad Martin Schröder Philippe Merle Massimo Levrero Paul Dény
author_sort	Natali Abeywickrama-Samarakoon
title	Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
title_short	Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
title_full	Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
title_fullStr	Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
title_full_unstemmed	Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
title_sort	hepatitis delta virus histone mimicry drives the recruitment of chromatin remodelers for viral rna replication
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0fa57c165bda4e6aa2ee90cc3d885e92
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Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication

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