Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication

Histone mimicry of viral components is a strategy to subvert host factors for virus replication. Here, the authors show that an acetylated histone-like motif of the small Hepatitis Delta Antigen (S-HDAg) interacts with the chromatin remodeler BAZ2B to recruit the DNA-dependent RNA polymerase II for...

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Main Authors: Natali Abeywickrama-Samarakoon, Jean-Claude Cortay, Camille Sureau, Susanne Müller, Dulce Alfaiate, Francesca Guerrieri, Apirat Chaikuad, Martin Schröder, Philippe Merle, Massimo Levrero, Paul Dény
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/0fa57c165bda4e6aa2ee90cc3d885e92
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