The aging lung

Erin M Lowery,1 Aleah L Brubaker,2 Erica Kuhlmann,1 Elizabeth J Kovacs31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine at Loyola University Medical Center, 2Loyola University Stritch School of Medicine, 3Department of Surgery, Loyola University Medical Center, Mayw...

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Autores principales:	Lowery EM, Brubaker AL, Kuhlmann E, Kovacs EJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Aging Lung pulmonary immunology COPD Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/0fb574a67c6741ac97d26fdf6e26075a
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spelling	oai:doaj.org-article:0fb574a67c6741ac97d26fdf6e26075a2021-12-02T00:54:30ZThe aging lung1178-1998https://doaj.org/article/0fb574a67c6741ac97d26fdf6e26075a2013-11-01T00:00:00Zhttps://www.dovepress.com/the-aging-lung-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Erin M Lowery,1 Aleah L Brubaker,2 Erica Kuhlmann,1 Elizabeth J Kovacs31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine at Loyola University Medical Center, 2Loyola University Stritch School of Medicine, 3Department of Surgery, Loyola University Medical Center, Maywood, IL, USAAbstract: There are many age-associated changes in the respiratory and pulmonary immune system. These changes include decreases in the volume of the thoracic cavity, reduced lung volumes, and alterations in the muscles that aid respiration. Muscle function on a cellular level in the aging population is less efficient. The elderly population has less pulmonary reserve, and cough strength is decreased in the elderly population due to anatomic changes and muscle atrophy. Clearance of particles from the lung through the mucociliary elevator is decreased and associated with ciliary dysfunction. Many complex changes in immunity with aging contribute to increased susceptibility to infections including a less robust immune response from both the innate and adaptive immune systems. Considering all of these age-related changes to the lungs, pulmonary disease has significant consequences for the aging population. Chronic lower respiratory tract disease is the third leading cause of death in people aged 65 years and older. With a large and growing aging population, it is critical to understand how the body changes with age and how this impacts the entire respiratory system. Understanding the aging process in the lung is necessary in order to provide optimal care to our aging population. This review focuses on the nonpathologic aging process in the lung, including structural changes, changes in muscle function, and pulmonary immunologic function, with special consideration of obstructive lung disease in the elderly.Keywords: aging, lung, pulmonary immunology, COPDLowery EMBrubaker ALKuhlmann EKovacs EJDove Medical PressarticleAgingLungpulmonary immunologyCOPDGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 8, Pp 1489-1496 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Aging Lung pulmonary immunology COPD Geriatrics RC952-954.6
spellingShingle	Aging Lung pulmonary immunology COPD Geriatrics RC952-954.6 Lowery EM Brubaker AL Kuhlmann E Kovacs EJ The aging lung
description	Erin M Lowery,1 Aleah L Brubaker,2 Erica Kuhlmann,1 Elizabeth J Kovacs31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine at Loyola University Medical Center, 2Loyola University Stritch School of Medicine, 3Department of Surgery, Loyola University Medical Center, Maywood, IL, USAAbstract: There are many age-associated changes in the respiratory and pulmonary immune system. These changes include decreases in the volume of the thoracic cavity, reduced lung volumes, and alterations in the muscles that aid respiration. Muscle function on a cellular level in the aging population is less efficient. The elderly population has less pulmonary reserve, and cough strength is decreased in the elderly population due to anatomic changes and muscle atrophy. Clearance of particles from the lung through the mucociliary elevator is decreased and associated with ciliary dysfunction. Many complex changes in immunity with aging contribute to increased susceptibility to infections including a less robust immune response from both the innate and adaptive immune systems. Considering all of these age-related changes to the lungs, pulmonary disease has significant consequences for the aging population. Chronic lower respiratory tract disease is the third leading cause of death in people aged 65 years and older. With a large and growing aging population, it is critical to understand how the body changes with age and how this impacts the entire respiratory system. Understanding the aging process in the lung is necessary in order to provide optimal care to our aging population. This review focuses on the nonpathologic aging process in the lung, including structural changes, changes in muscle function, and pulmonary immunologic function, with special consideration of obstructive lung disease in the elderly.Keywords: aging, lung, pulmonary immunology, COPD
format	article
author	Lowery EM Brubaker AL Kuhlmann E Kovacs EJ
author_facet	Lowery EM Brubaker AL Kuhlmann E Kovacs EJ
author_sort	Lowery EM
title	The aging lung
title_short	The aging lung
title_full	The aging lung
title_fullStr	The aging lung
title_full_unstemmed	The aging lung
title_sort	aging lung
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/0fb574a67c6741ac97d26fdf6e26075a
work_keys_str_mv	AT loweryem theaginglung AT brubakeral theaginglung AT kuhlmanne theaginglung AT kovacsej theaginglung AT loweryem aginglung AT brubakeral aginglung AT kuhlmanne aginglung AT kovacsej aginglung
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The aging lung

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