Phenolics Profiling and Free Radical Scavenging Activity of Annona muricata, Gynura procumbens, and Typhonium flagelliforme Leaves Extract

The leaves of Annona muricata (sirsak), Gynura procumbens (sambung nyawa), and Typhonium flagelliforme (keladi tikus) have been used as traditional medicines in Indonesia. This study aims to determine the antioxidant capacity and putatively identified phenolics from the leaves of three medicinal pla...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Dewi Anggraini Septaningsih, Amalia Yunita, Cecep Abdurohman Putra, Irma Herawati Suparto, Suminar Setiati Achmadi, Rudi Heryanto, Mohamad Rafi
Formato:	article
Lenguaje:	EN
Publicado:	Department of Chemistry, Universitas Gadjah Mada 2021
Materias:	annona muricata radical scavenging activity gynura procumbens phenolics profiling typhonium flagelliforme uhplc-q-orbitrap hrms Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/0fc03d4c7fb74411bb863bc2b82c3115
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0fc03d4c7fb74411bb863bc2b82c3115
record_format	dspace
spelling	oai:doaj.org-article:0fc03d4c7fb74411bb863bc2b82c31152021-12-02T18:02:39ZPhenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract1411-94202460-157810.22146/ijc.62124https://doaj.org/article/0fc03d4c7fb74411bb863bc2b82c31152021-09-01T00:00:00Zhttps://jurnal.ugm.ac.id/ijc/article/view/62124https://doaj.org/toc/1411-9420https://doaj.org/toc/2460-1578The leaves of Annona muricata (sirsak), Gynura procumbens (sambung nyawa), and Typhonium flagelliforme (keladi tikus) have been used as traditional medicines in Indonesia. This study aims to determine the antioxidant capacity and putatively identified phenolics from the leaves of three medicinal plants forementioned above. We used the DPPH (2,2-diphenyl-1-picrylhydrazyl) method for measuring radical scavenging (antioxidant assay) while the phenolics profiling was determined using UHPLC-Q-Orbitrap HRMS. The results showed that the percentage of radical scavenging activity of G. procumbens leaves extract in ethanol was higher than the other two plants. Phenolics profiling of the three medicinal plants was identified with 38 compounds belonging to flavones and flavanols hydroxycinnamic acid, and several other groups. The number of metabolites identified putatively was 12, 31, and 19 metabolites in the extracts of A. muricata, G. procumbens, and T. flagelliforme, respectively. The results confirmed the correlation between the phenolics presence and the antioxidant capacity of three plants used in this study.Dewi Anggraini SeptaningsihAmalia YunitaCecep Abdurohman PutraIrma Herawati SupartoSuminar Setiati AchmadiRudi HeryantoMohamad RafiDepartment of Chemistry, Universitas Gadjah Madaarticleannona muricataradical scavenging activitygynura procumbensphenolics profilingtyphonium flagelliformeuhplc-q-orbitrap hrmsChemistryQD1-999ENIndonesian Journal of Chemistry, Vol 21, Iss 5, Pp 1140-1147 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	annona muricata radical scavenging activity gynura procumbens phenolics profiling typhonium flagelliforme uhplc-q-orbitrap hrms Chemistry QD1-999
spellingShingle	annona muricata radical scavenging activity gynura procumbens phenolics profiling typhonium flagelliforme uhplc-q-orbitrap hrms Chemistry QD1-999 Dewi Anggraini Septaningsih Amalia Yunita Cecep Abdurohman Putra Irma Herawati Suparto Suminar Setiati Achmadi Rudi Heryanto Mohamad Rafi Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract
description	The leaves of Annona muricata (sirsak), Gynura procumbens (sambung nyawa), and Typhonium flagelliforme (keladi tikus) have been used as traditional medicines in Indonesia. This study aims to determine the antioxidant capacity and putatively identified phenolics from the leaves of three medicinal plants forementioned above. We used the DPPH (2,2-diphenyl-1-picrylhydrazyl) method for measuring radical scavenging (antioxidant assay) while the phenolics profiling was determined using UHPLC-Q-Orbitrap HRMS. The results showed that the percentage of radical scavenging activity of G. procumbens leaves extract in ethanol was higher than the other two plants. Phenolics profiling of the three medicinal plants was identified with 38 compounds belonging to flavones and flavanols hydroxycinnamic acid, and several other groups. The number of metabolites identified putatively was 12, 31, and 19 metabolites in the extracts of A. muricata, G. procumbens, and T. flagelliforme, respectively. The results confirmed the correlation between the phenolics presence and the antioxidant capacity of three plants used in this study.
format	article
author	Dewi Anggraini Septaningsih Amalia Yunita Cecep Abdurohman Putra Irma Herawati Suparto Suminar Setiati Achmadi Rudi Heryanto Mohamad Rafi
author_facet	Dewi Anggraini Septaningsih Amalia Yunita Cecep Abdurohman Putra Irma Herawati Suparto Suminar Setiati Achmadi Rudi Heryanto Mohamad Rafi
author_sort	Dewi Anggraini Septaningsih
title	Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract
title_short	Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract
title_full	Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract
title_fullStr	Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract
title_full_unstemmed	Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract
title_sort	phenolics profiling and free radical scavenging activity of <i>annona muricata</i>, <i>gynura procumbens</i>, and <i>typhonium flagelliforme</i> leaves extract
publisher	Department of Chemistry, Universitas Gadjah Mada
publishDate	2021
url	https://doaj.org/article/0fc03d4c7fb74411bb863bc2b82c3115
work_keys_str_mv	AT dewianggrainiseptaningsih phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract AT amaliayunita phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract AT cecepabdurohmanputra phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract AT irmaherawatisuparto phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract AT suminarsetiatiachmadi phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract AT rudiheryanto phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract AT mohamadrafi phenolicsprofilingandfreeradicalscavengingactivityofiannonamuricataiigynuraprocumbensiandityphoniumflagelliformeileavesextract
_version_	1718378851266985984

Phenolics Profiling and Free Radical Scavenging Activity of <i>Annona muricata</i>, <i>Gynura procumbens</i>, and <i>Typhonium flagelliforme</i> Leaves Extract

Ejemplares similares