Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

There are only a few examples of nanocarriers that can transport bioactive substances across the blood-brain barrier. Here the authors show that by rapid glycaemic increase the accumulation of a glucosylated nanocarrier in the brain can be controlled.

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Autores principales: Y. Anraku, H. Kuwahara, Y. Fukusato, A. Mizoguchi, T. Ishii, K. Nitta, Y. Matsumoto, K. Toh, K. Miyata, S. Uchida, K. Nishina, K. Osada, K. Itaka, N. Nishiyama, H. Mizusawa, T. Yamasoba, T. Yokota, K. Kataoka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0fc143dfc7464c2e803e239b8d4ccb42
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spelling oai:doaj.org-article:0fc143dfc7464c2e803e239b8d4ccb422021-12-02T14:42:28ZGlycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain10.1038/s41467-017-00952-32041-1723https://doaj.org/article/0fc143dfc7464c2e803e239b8d4ccb422017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00952-3https://doaj.org/toc/2041-1723There are only a few examples of nanocarriers that can transport bioactive substances across the blood-brain barrier. Here the authors show that by rapid glycaemic increase the accumulation of a glucosylated nanocarrier in the brain can be controlled.Y. AnrakuH. KuwaharaY. FukusatoA. MizoguchiT. IshiiK. NittaY. MatsumotoK. TohK. MiyataS. UchidaK. NishinaK. OsadaK. ItakaN. NishiyamaH. MizusawaT. YamasobaT. YokotaK. KataokaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Y. Anraku
H. Kuwahara
Y. Fukusato
A. Mizoguchi
T. Ishii
K. Nitta
Y. Matsumoto
K. Toh
K. Miyata
S. Uchida
K. Nishina
K. Osada
K. Itaka
N. Nishiyama
H. Mizusawa
T. Yamasoba
T. Yokota
K. Kataoka
Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
description There are only a few examples of nanocarriers that can transport bioactive substances across the blood-brain barrier. Here the authors show that by rapid glycaemic increase the accumulation of a glucosylated nanocarrier in the brain can be controlled.
format article
author Y. Anraku
H. Kuwahara
Y. Fukusato
A. Mizoguchi
T. Ishii
K. Nitta
Y. Matsumoto
K. Toh
K. Miyata
S. Uchida
K. Nishina
K. Osada
K. Itaka
N. Nishiyama
H. Mizusawa
T. Yamasoba
T. Yokota
K. Kataoka
author_facet Y. Anraku
H. Kuwahara
Y. Fukusato
A. Mizoguchi
T. Ishii
K. Nitta
Y. Matsumoto
K. Toh
K. Miyata
S. Uchida
K. Nishina
K. Osada
K. Itaka
N. Nishiyama
H. Mizusawa
T. Yamasoba
T. Yokota
K. Kataoka
author_sort Y. Anraku
title Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
title_short Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
title_full Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
title_fullStr Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
title_full_unstemmed Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain
title_sort glycaemic control boosts glucosylated nanocarrier crossing the bbb into the brain
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/0fc143dfc7464c2e803e239b8d4ccb42
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