Functional characterization of a loss-of-function mutant I324M of arginine vasopressin receptor 2 in X-linked nephrogenic diabetes insipidus
Abstract X-linked nephrogenic diabetes insipidus (X-linked NDI) is a rare inherited disease mainly caused by lost-of-function mutations in human AVPR2 gene encoding arginine vasopressin receptor 2 (V2R). Our focus of the current study is on exploration of the functional and biochemical properties of...
Guardado en:
Autores principales: | Lixia Wang, Weihong Guo, Chunyun Fang, Wenli Feng, Yumeng Huang, Xiaona Zhang, Ming Liu, Jingqiu Cui |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0fc457740b264d7d9a3ec219ff97a940 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus
por: Fumiaki Ando, et al.
Publicado: (2018) -
Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus
por: Takafumi Suzuki, et al.
Publicado: (2017) -
Atorvastatin does not ameliorate nephrogenic diabetes insipidus induced by lithium or potassium depletion in mice
por: Maria L. Thomsen, et al.
Publicado: (2021) -
Transient Antidiuretic Hormone Insufficiency Caused by Severe Hyperosmolar Hyperglycemic Syndrome Based on Nephrogenic Diabetes Insipidus
por: Mizuki Gobaru, MD, et al.
Publicado: (2021) -
DLK1 is a somato-dendritic protein expressed in hypothalamic arginine-vasopressin and oxytocin neurons.
por: Carine Villanueva, et al.
Publicado: (2012)