Risk factors for pancreatitis and pancreatic cancer

Aim. To identify and compare the frequency of alcohol consumption, tobacco smoking, levels of main macronutrients, vitamins and mineral elements consumption in patients with acute (AP) and chronic pancreatitis (CP) and pancreatic cancer (PC). Materials and methods. At the observational clinical c...

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Autores principales:	Irina N. Grigor’eva, Olga V. Efimova
Formato:	article
Lenguaje:	RU
Publicado:	"Consilium Medicum" Publishing house 2021
Materias:	acute pancreatitis chronic pancreatitis pancreatic cancer tobacco smoking alcohol consumption nutrition Medicine R
Acceso en línea:	https://doaj.org/article/0fc69fd20cdd49b1adc729cc11d5b945
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spelling	oai:doaj.org-article:0fc69fd20cdd49b1adc729cc11d5b9452021-12-01T12:22:36ZRisk factors for pancreatitis and pancreatic cancer0040-36602309-534210.26442/00403660.2021.08.200970https://doaj.org/article/0fc69fd20cdd49b1adc729cc11d5b9452021-08-01T00:00:00Zhttps://ter-arkhiv.ru/0040-3660/article/viewFile/79419/60067https://doaj.org/toc/0040-3660https://doaj.org/toc/2309-5342Aim. To identify and compare the frequency of alcohol consumption, tobacco smoking, levels of main macronutrients, vitamins and mineral elements consumption in patients with acute (AP) and chronic pancreatitis (CP) and pancreatic cancer (PC). Materials and methods. At the observational clinical cross-sectional uncontrolled case-study 65 patients with AP or CP (group 1) and 45 patients with PC (group 2) were examined. A survey of patients was carried out: questionnaire on tobacco smoking, a frequency questionnaire on alcohol consumption, a questionnaire for assessing the frequency of food consumption. Results. The frequency of smoking (33.8, 20.0%; p0.05), alcohol consumption 1 times/week during the last year (21.5, 15.6%; p0.05) did not differ significantly between the two groups. The highest consumption rates of total, vegetable, animal protein, total carbohydrates, refined sugar, animal fat, cholesterol, MUFA, dietary fiber, vitamins (-carotene, vitamin B1, B2, C, PP), mineral elements (iron, potassium, calcium, magnesium, sodium, phosphorus) and the daily energy content of the diet were determined in PC than in the AP and CP group. Among patients of group 1, deficient intake of fat-soluble vitamin A (93.3, 54.8%; p=0.009) and vitamin E (80.0, 48.4%; p=0.041) was more common in the subgroup of patients with excretory pancreatic insufficiency than without it, and the chance of having hypercholesterolemia was associated with a deficient intake of vitamin E [Ex(B)=3.3, 95% CI 1.59.3; p=0.027]. Conclusion. There were no differences in the frequency of smoking and alcohol consumption between patients with AP and CP and PC. The highest indices of the main macronutrients, daily energy content of the diet, micronutrients (except for vitamins A, E) were found in PC than in the group of patients with AP and CP. Among patients with AP and CP with excretory pancreatic insufficiency, a lower intake of fat-soluble vitamins was noted and associations of hypercholesterolemia with deficient intake of vitamin E were obtained.Irina N. Grigor’evaOlga V. Efimova"Consilium Medicum" Publishing housearticleacute pancreatitischronic pancreatitispancreatic cancertobacco smokingalcohol consumptionnutritionMedicineRRUТерапевтический архив, Vol 93, Iss 8, Pp 875-882 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	acute pancreatitis chronic pancreatitis pancreatic cancer tobacco smoking alcohol consumption nutrition Medicine R
spellingShingle	acute pancreatitis chronic pancreatitis pancreatic cancer tobacco smoking alcohol consumption nutrition Medicine R Irina N. Grigor’eva Olga V. Efimova Risk factors for pancreatitis and pancreatic cancer
description	Aim. To identify and compare the frequency of alcohol consumption, tobacco smoking, levels of main macronutrients, vitamins and mineral elements consumption in patients with acute (AP) and chronic pancreatitis (CP) and pancreatic cancer (PC). Materials and methods. At the observational clinical cross-sectional uncontrolled case-study 65 patients with AP or CP (group 1) and 45 patients with PC (group 2) were examined. A survey of patients was carried out: questionnaire on tobacco smoking, a frequency questionnaire on alcohol consumption, a questionnaire for assessing the frequency of food consumption. Results. The frequency of smoking (33.8, 20.0%; p0.05), alcohol consumption 1 times/week during the last year (21.5, 15.6%; p0.05) did not differ significantly between the two groups. The highest consumption rates of total, vegetable, animal protein, total carbohydrates, refined sugar, animal fat, cholesterol, MUFA, dietary fiber, vitamins (-carotene, vitamin B1, B2, C, PP), mineral elements (iron, potassium, calcium, magnesium, sodium, phosphorus) and the daily energy content of the diet were determined in PC than in the AP and CP group. Among patients of group 1, deficient intake of fat-soluble vitamin A (93.3, 54.8%; p=0.009) and vitamin E (80.0, 48.4%; p=0.041) was more common in the subgroup of patients with excretory pancreatic insufficiency than without it, and the chance of having hypercholesterolemia was associated with a deficient intake of vitamin E [Ex(B)=3.3, 95% CI 1.59.3; p=0.027]. Conclusion. There were no differences in the frequency of smoking and alcohol consumption between patients with AP and CP and PC. The highest indices of the main macronutrients, daily energy content of the diet, micronutrients (except for vitamins A, E) were found in PC than in the group of patients with AP and CP. Among patients with AP and CP with excretory pancreatic insufficiency, a lower intake of fat-soluble vitamins was noted and associations of hypercholesterolemia with deficient intake of vitamin E were obtained.
format	article
author	Irina N. Grigor’eva Olga V. Efimova
author_facet	Irina N. Grigor’eva Olga V. Efimova
author_sort	Irina N. Grigor’eva
title	Risk factors for pancreatitis and pancreatic cancer
title_short	Risk factors for pancreatitis and pancreatic cancer
title_full	Risk factors for pancreatitis and pancreatic cancer
title_fullStr	Risk factors for pancreatitis and pancreatic cancer
title_full_unstemmed	Risk factors for pancreatitis and pancreatic cancer
title_sort	risk factors for pancreatitis and pancreatic cancer
publisher	"Consilium Medicum" Publishing house
publishDate	2021
url	https://doaj.org/article/0fc69fd20cdd49b1adc729cc11d5b945
work_keys_str_mv	AT irinangrigoreva riskfactorsforpancreatitisandpancreaticcancer AT olgavefimova riskfactorsforpancreatitisandpancreaticcancer
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Risk factors for pancreatitis and pancreatic cancer

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