Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study

Shuichiro Tachi,1,2 Miki Asamizu,2 Yoshihiro Uchida,1–3 Shigemasa Katayama,1,2 Mayu Naruse,1 Jiro Masuya,1,3 Masahiko Ichiki,1 Takeshi Inoue1 1Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan; 2Seijin Hospital, Tokyo 121-0815, Japan; 3Department of Psychiatry, Ibar...

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Autores principales:	Tachi S, Asamizu M, Uchida Y, Katayama S, Naruse M, Masuya J, Ichiki M, Inoue T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Victimization Neuroticism Depression Major Depressive Disorder Path analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/0fce78f03d0b487fb09678c00e52a2ec
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spelling	oai:doaj.org-article:0fce78f03d0b487fb09678c00e52a2ec2021-12-02T04:04:26ZVictimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study1178-2021https://doaj.org/article/0fce78f03d0b487fb09678c00e52a2ec2019-10-01T00:00:00Zhttps://www.dovepress.com/victimization-in-childhood-affects-depression-in-adulthood-via-neuroti-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Shuichiro Tachi,1,2 Miki Asamizu,2 Yoshihiro Uchida,1–3 Shigemasa Katayama,1,2 Mayu Naruse,1 Jiro Masuya,1,3 Masahiko Ichiki,1 Takeshi Inoue1 1Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan; 2Seijin Hospital, Tokyo 121-0815, Japan; 3Department of Psychiatry, Ibaraki Medical Center, Tokyo Medical University, Ibaraki 300-0395, JapanCorrespondence: Takeshi InoueDepartment of Psychiatry, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, JapanTel +81 3 3342 6111 (Ext. 5754)Fax +81 3 3340 4499Email tinoue@tokyo-med.ac.jpBackground: Adverse experiences, such as low care, overprotection, or abuse in childhood increase the likelihood of depression via their effects on personality traits. Similarly, being victimized in childhood may affect the likelihood of depression via personality traits. In this case-control study, we hypothesized that being victimized in childhood is associated with depression in adulthood via its effect on neuroticism, and verified this hypothesis using path analysis.Subjects and methods: Eighty-two major depressive disorder (MDD) patients and 350 age-and-sex matched healthy controls completed self-administered questionnaires of demographic data, Patient Health Questionnaire-9, neuroticism, and victimization. The association between victimization, neuroticism, and depressive symptoms or having major depression was investigated by path analysis.Results: Multiple group path analysis, in which depressive symptoms were considered as dependent variables, showed that the direct effect of victimization in childhood on depressive symptoms was not statistically significant in either healthy controls or MDD patients (standardized path coefficient: 0.079 and 0.084, respectively), but their indirect effects via neuroticism were statistically significant (standardized path coefficient: 0.059 and 0.141, respectively). Path analysis, in which the distinction between healthy controls and MDD patients was a dependent variable, showed that both direct effects and indirect effects of victimization in childhood via neuroticism on the distinction between healthy controls and MDD patients were statistically significant (standardized path coefficient: 0.186 and 0.164, respectively).Limitations: Recall bias and the relatively small number of MDD patients are limitations of this study. Because it was a case-control survey, this study could not make any conclusions regarding causal associations.Conclusion: This study suggests the possibility of causal associations between victimization in childhood and depressive symptoms or MDD in adulthood, and the mediation of this association by neuroticism.Keywords: victimization, neuroticism, depression, major depressive disorder, path analysisTachi SAsamizu MUchida YKatayama SNaruse MMasuya JIchiki MInoue TDove Medical PressarticleVictimizationNeuroticismDepressionMajor Depressive DisorderPath analysisNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 2835-2841 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Victimization Neuroticism Depression Major Depressive Disorder Path analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Victimization Neuroticism Depression Major Depressive Disorder Path analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Tachi S Asamizu M Uchida Y Katayama S Naruse M Masuya J Ichiki M Inoue T Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study
description	Shuichiro Tachi,1,2 Miki Asamizu,2 Yoshihiro Uchida,1–3 Shigemasa Katayama,1,2 Mayu Naruse,1 Jiro Masuya,1,3 Masahiko Ichiki,1 Takeshi Inoue1 1Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan; 2Seijin Hospital, Tokyo 121-0815, Japan; 3Department of Psychiatry, Ibaraki Medical Center, Tokyo Medical University, Ibaraki 300-0395, JapanCorrespondence: Takeshi InoueDepartment of Psychiatry, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, JapanTel +81 3 3342 6111 (Ext. 5754)Fax +81 3 3340 4499Email tinoue@tokyo-med.ac.jpBackground: Adverse experiences, such as low care, overprotection, or abuse in childhood increase the likelihood of depression via their effects on personality traits. Similarly, being victimized in childhood may affect the likelihood of depression via personality traits. In this case-control study, we hypothesized that being victimized in childhood is associated with depression in adulthood via its effect on neuroticism, and verified this hypothesis using path analysis.Subjects and methods: Eighty-two major depressive disorder (MDD) patients and 350 age-and-sex matched healthy controls completed self-administered questionnaires of demographic data, Patient Health Questionnaire-9, neuroticism, and victimization. The association between victimization, neuroticism, and depressive symptoms or having major depression was investigated by path analysis.Results: Multiple group path analysis, in which depressive symptoms were considered as dependent variables, showed that the direct effect of victimization in childhood on depressive symptoms was not statistically significant in either healthy controls or MDD patients (standardized path coefficient: 0.079 and 0.084, respectively), but their indirect effects via neuroticism were statistically significant (standardized path coefficient: 0.059 and 0.141, respectively). Path analysis, in which the distinction between healthy controls and MDD patients was a dependent variable, showed that both direct effects and indirect effects of victimization in childhood via neuroticism on the distinction between healthy controls and MDD patients were statistically significant (standardized path coefficient: 0.186 and 0.164, respectively).Limitations: Recall bias and the relatively small number of MDD patients are limitations of this study. Because it was a case-control survey, this study could not make any conclusions regarding causal associations.Conclusion: This study suggests the possibility of causal associations between victimization in childhood and depressive symptoms or MDD in adulthood, and the mediation of this association by neuroticism.Keywords: victimization, neuroticism, depression, major depressive disorder, path analysis
format	article
author	Tachi S Asamizu M Uchida Y Katayama S Naruse M Masuya J Ichiki M Inoue T
author_facet	Tachi S Asamizu M Uchida Y Katayama S Naruse M Masuya J Ichiki M Inoue T
author_sort	Tachi S
title	Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study
title_short	Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study
title_full	Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study
title_fullStr	Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study
title_full_unstemmed	Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study
title_sort	victimization in childhood affects depression in adulthood via neuroticism: a path analysis study
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/0fce78f03d0b487fb09678c00e52a2ec
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Victimization In Childhood Affects Depression In Adulthood Via Neuroticism: A Path Analysis Study

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