NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data

Montemurro et al. present NetTCR-2.0, a convolutional neural network-based tool for predicting the interactions between T cell receptors and MHC-peptide complexes. This tool demonstrates that the best predictions are made when CDR3 α or CDR3 β binding data are used in combination.

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Auteurs principaux: Alessandro Montemurro, Viktoria Schuster, Helle Rus Povlsen, Amalie Kai Bentzen, Vanessa Jurtz, William D. Chronister, Austin Crinklaw, Sine R. Hadrup, Ole Winther, Bjoern Peters, Leon Eyrich Jessen, Morten Nielsen
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/0fd24268ab1c4d9e95f4d96aaa1b710a
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