Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor

It is unclear how bacterial cells adapt the reversible switching of flagellar motor rotation to environments of different viscosities. Here, Antani et al. show that flagellar mechanosensors allosterically control the motor’s binding affinity for the chemotaxis response regulator, CheY-P, to adapt fl...

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Autores principales: Jyot D. Antani, Rachit Gupta, Annie H. Lee, Kathy Y. Rhee, Michael D. Manson, Pushkar P. Lele
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c7
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Sumario:It is unclear how bacterial cells adapt the reversible switching of flagellar motor rotation to environments of different viscosities. Here, Antani et al. show that flagellar mechanosensors allosterically control the motor’s binding affinity for the chemotaxis response regulator, CheY-P, to adapt flagellar switching over varying viscous loads.