Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor

It is unclear how bacterial cells adapt the reversible switching of flagellar motor rotation to environments of different viscosities. Here, Antani et al. show that flagellar mechanosensors allosterically control the motor’s binding affinity for the chemotaxis response regulator, CheY-P, to adapt fl...

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Autores principales:	Jyot D. Antani, Rachit Gupta, Annie H. Lee, Kathy Y. Rhee, Michael D. Manson, Pushkar P. Lele
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c7
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spelling	oai:doaj.org-article:0fd537e0ea6a4785bce616b5c69954c72021-12-02T18:33:48ZMechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor10.1038/s41467-021-25774-22041-1723https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c72021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25774-2https://doaj.org/toc/2041-1723It is unclear how bacterial cells adapt the reversible switching of flagellar motor rotation to environments of different viscosities. Here, Antani et al. show that flagellar mechanosensors allosterically control the motor’s binding affinity for the chemotaxis response regulator, CheY-P, to adapt flagellar switching over varying viscous loads.Jyot D. AntaniRachit GuptaAnnie H. LeeKathy Y. RheeMichael D. MansonPushkar P. LeleNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jyot D. Antani Rachit Gupta Annie H. Lee Kathy Y. Rhee Michael D. Manson Pushkar P. Lele Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor
description	It is unclear how bacterial cells adapt the reversible switching of flagellar motor rotation to environments of different viscosities. Here, Antani et al. show that flagellar mechanosensors allosterically control the motor’s binding affinity for the chemotaxis response regulator, CheY-P, to adapt flagellar switching over varying viscous loads.
format	article
author	Jyot D. Antani Rachit Gupta Annie H. Lee Kathy Y. Rhee Michael D. Manson Pushkar P. Lele
author_facet	Jyot D. Antani Rachit Gupta Annie H. Lee Kathy Y. Rhee Michael D. Manson Pushkar P. Lele
author_sort	Jyot D. Antani
title	Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor
title_short	Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor
title_full	Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor
title_fullStr	Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor
title_full_unstemmed	Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor
title_sort	mechanosensitive recruitment of stator units promotes binding of the response regulator chey-p to the flagellar motor
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0fd537e0ea6a4785bce616b5c69954c7
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Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor

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