A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

Oligodendroglioma poses a biological conundrum for malignant adult human gliomas: it is a tumor type that is universally incurable for patients, and yet, only a few of the human tumors have been established as cell populations in vitro or as intracranial xenografts in vivo. Their survival, thus, may...

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Main Authors: Barbara Klink, Hrvoje Miletic, Daniel Stieber, Peter C Huszthy, Jaime Alberto Campos Valenzuela, Jörg Balss, Jian Wang, Manja Schubert, Per Øystein Sakariassen, Terje Sundstrøm, Anja Torsvik, Mads Aarhus, Rupavathana Mahesparan, Andreas von Deimling, Lars Kaderali, Simone P Niclou, Evelin Schröck, Rolf Bjerkvig, Janice M Nigro
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/0fde4b9e5f4a4bf1977638549aa2787d
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https://doaj.org/article/0fde4b9e5f4a4bf1977638549aa2787d

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