Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts
The early steps of ribosome assembly occur co-transcriptionally on the nascent ribosomal RNA. Here the authors demonstrate an approach that allows simultaneous monitoring of transcription and ribosomal protein assembly at the single-molecule level in real time.
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Nature Portfolio
2018
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oai:doaj.org-article:0fe00cc7c750481fa2a7c9346d042e432021-12-02T15:34:40ZReal-time assembly of ribonucleoprotein complexes on nascent RNA transcripts10.1038/s41467-018-07423-32041-1723https://doaj.org/article/0fe00cc7c750481fa2a7c9346d042e432018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07423-3https://doaj.org/toc/2041-1723The early steps of ribosome assembly occur co-transcriptionally on the nascent ribosomal RNA. Here the authors demonstrate an approach that allows simultaneous monitoring of transcription and ribosomal protein assembly at the single-molecule level in real time.Olivier DussGalina A. StepanyukAnnette GrotSeán E. O’LearyJoseph D. PuglisiJames R. WilliamsonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q |
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Science Q Olivier Duss Galina A. Stepanyuk Annette Grot Seán E. O’Leary Joseph D. Puglisi James R. Williamson Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts |
description |
The early steps of ribosome assembly occur co-transcriptionally on the nascent ribosomal RNA. Here the authors demonstrate an approach that allows simultaneous monitoring of transcription and ribosomal protein assembly at the single-molecule level in real time. |
format |
article |
author |
Olivier Duss Galina A. Stepanyuk Annette Grot Seán E. O’Leary Joseph D. Puglisi James R. Williamson |
author_facet |
Olivier Duss Galina A. Stepanyuk Annette Grot Seán E. O’Leary Joseph D. Puglisi James R. Williamson |
author_sort |
Olivier Duss |
title |
Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts |
title_short |
Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts |
title_full |
Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts |
title_fullStr |
Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts |
title_full_unstemmed |
Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts |
title_sort |
real-time assembly of ribonucleoprotein complexes on nascent rna transcripts |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/0fe00cc7c750481fa2a7c9346d042e43 |
work_keys_str_mv |
AT olivierduss realtimeassemblyofribonucleoproteincomplexesonnascentrnatranscripts AT galinaastepanyuk realtimeassemblyofribonucleoproteincomplexesonnascentrnatranscripts AT annettegrot realtimeassemblyofribonucleoproteincomplexesonnascentrnatranscripts AT seaneoleary realtimeassemblyofribonucleoproteincomplexesonnascentrnatranscripts AT josephdpuglisi realtimeassemblyofribonucleoproteincomplexesonnascentrnatranscripts AT jamesrwilliamson realtimeassemblyofribonucleoproteincomplexesonnascentrnatranscripts |
_version_ |
1718386764115083264 |