Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy
Bacterial biofilms rely on shared extracellular polymeric substances (EPS) and are often highly tolerant to antibiotics. Here, the authors show in in vitro experiments that Salmonella does not evolve resistance to EPS inhibition because such strains are outcompeted by a susceptible strain under inhi...
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Nature Portfolio
2020
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oai:doaj.org-article:0fe92426ee98474f992afb748d21b64e2021-12-02T15:37:17ZInhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy10.1038/s41467-019-13660-x2041-1723https://doaj.org/article/0fe92426ee98474f992afb748d21b64e2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13660-xhttps://doaj.org/toc/2041-1723Bacterial biofilms rely on shared extracellular polymeric substances (EPS) and are often highly tolerant to antibiotics. Here, the authors show in in vitro experiments that Salmonella does not evolve resistance to EPS inhibition because such strains are outcompeted by a susceptible strain under inhibitor treatment.Lise DieltjensKenny AppermansMaries LissensBram LoriesWook KimErik V. Van der EyckenKevin R. FosterHans P. SteenackersNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q |
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Science Q Lise Dieltjens Kenny Appermans Maries Lissens Bram Lories Wook Kim Erik V. Van der Eycken Kevin R. Foster Hans P. Steenackers Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
description |
Bacterial biofilms rely on shared extracellular polymeric substances (EPS) and are often highly tolerant to antibiotics. Here, the authors show in in vitro experiments that Salmonella does not evolve resistance to EPS inhibition because such strains are outcompeted by a susceptible strain under inhibitor treatment. |
format |
article |
author |
Lise Dieltjens Kenny Appermans Maries Lissens Bram Lories Wook Kim Erik V. Van der Eycken Kevin R. Foster Hans P. Steenackers |
author_facet |
Lise Dieltjens Kenny Appermans Maries Lissens Bram Lories Wook Kim Erik V. Van der Eycken Kevin R. Foster Hans P. Steenackers |
author_sort |
Lise Dieltjens |
title |
Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
title_short |
Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
title_full |
Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
title_fullStr |
Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
title_full_unstemmed |
Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
title_sort |
inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/0fe92426ee98474f992afb748d21b64e |
work_keys_str_mv |
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_version_ |
1718386214595198976 |