Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes

Sidra Zafar,1 MA Rehman Siddiqui,2,3 Rida Shahzad1 1Medical College, Aga Khan University Hospital, 2Department of Ophthalmology, Shahzad Eye Hospital, 3South City Hospital, Karachi, Pakistan Purpose: Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study w...

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Autores principales: Zafar S, Siddiqui MAR, Shahzad R
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Lenguaje:EN
Publicado: Dove Medical Press 2016
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spelling oai:doaj.org-article:0ff874b1120641fe89052c07384889b62021-12-02T02:59:47ZComparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes1177-5483https://doaj.org/article/0ff874b1120641fe89052c07384889b62016-11-01T00:00:00Zhttps://www.dovepress.com/comparison-of-choroidal-thickness-measurements-between-spectral-domain-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Sidra Zafar,1 MA Rehman Siddiqui,2,3 Rida Shahzad1 1Medical College, Aga Khan University Hospital, 2Department of Ophthalmology, Shahzad Eye Hospital, 3South City Hospital, Karachi, Pakistan Purpose: Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study was to compare SFCT measurements between Topcon 3D 2000 spectral-domain optical coherence tomography (SD-OCT) and Topcon swept-source OCT (SS-OCT), with different laser wavelengths, in normal and diseased populations. Materials and methods: This was a prospective, cross-sectional, noninterventional study including 27 normal volunteers and 27 participants with retinal disease. OCT scans were performed sequentially and under standardized conditions using both SD-OCT and SS-OCT. The OCT scans were evaluated by two independent graders. Paired t-tests and intraclass correlation coefficients (ICCs) were used to assess the statistically significant difference between SFCT measurements as measured by the two devices. Results: Mean SFCT measurements for all 54 participants were 264.9±103.1 µm using SD-OCT (range: 47–470 µm) and 278.5±110.5 µm using SS-OCT (range: 56–502 µm), with an inter-device ICC of 0.850. Greater variability was noted in the diseased eyes. Inter-device ICCs were 0.870 (95% CI; 0.760–0.924) and 0.840 (95% CI; 0.654–0.930) for normal and diseased eyes, respectively. However, the difference was not statistically significant (P=0.132). Conclusion: Both machines reliably measure SFCT. Larger studies are needed to confirm these findings. Keywords: choroidal imaging, diseased, normal, SD-OCT, SS-OCTZafar SSiddiqui MARShahzad RDove Medical PressarticleKeywords: Choroidal imagingdiseasednormalSD-OCTSS-OCT.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 2271-2276 (2016)
institution DOAJ
collection DOAJ
language EN
topic Keywords: Choroidal imaging
diseased
normal
SD-OCT
SS-OCT.
Ophthalmology
RE1-994
spellingShingle Keywords: Choroidal imaging
diseased
normal
SD-OCT
SS-OCT.
Ophthalmology
RE1-994
Zafar S
Siddiqui MAR
Shahzad R
Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
description Sidra Zafar,1 MA Rehman Siddiqui,2,3 Rida Shahzad1 1Medical College, Aga Khan University Hospital, 2Department of Ophthalmology, Shahzad Eye Hospital, 3South City Hospital, Karachi, Pakistan Purpose: Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study was to compare SFCT measurements between Topcon 3D 2000 spectral-domain optical coherence tomography (SD-OCT) and Topcon swept-source OCT (SS-OCT), with different laser wavelengths, in normal and diseased populations. Materials and methods: This was a prospective, cross-sectional, noninterventional study including 27 normal volunteers and 27 participants with retinal disease. OCT scans were performed sequentially and under standardized conditions using both SD-OCT and SS-OCT. The OCT scans were evaluated by two independent graders. Paired t-tests and intraclass correlation coefficients (ICCs) were used to assess the statistically significant difference between SFCT measurements as measured by the two devices. Results: Mean SFCT measurements for all 54 participants were 264.9±103.1 µm using SD-OCT (range: 47–470 µm) and 278.5±110.5 µm using SS-OCT (range: 56–502 µm), with an inter-device ICC of 0.850. Greater variability was noted in the diseased eyes. Inter-device ICCs were 0.870 (95% CI; 0.760–0.924) and 0.840 (95% CI; 0.654–0.930) for normal and diseased eyes, respectively. However, the difference was not statistically significant (P=0.132). Conclusion: Both machines reliably measure SFCT. Larger studies are needed to confirm these findings. Keywords: choroidal imaging, diseased, normal, SD-OCT, SS-OCT
format article
author Zafar S
Siddiqui MAR
Shahzad R
author_facet Zafar S
Siddiqui MAR
Shahzad R
author_sort Zafar S
title Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
title_short Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
title_full Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
title_fullStr Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
title_full_unstemmed Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
title_sort comparison of choroidal thickness measurements between spectral-domain oct and swept-source oct in normal and diseased eyes
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/0ff874b1120641fe89052c07384889b6
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AT siddiquimar comparisonofchoroidalthicknessmeasurementsbetweenspectraldomainoctandsweptsourceoctinnormalanddiseasedeyes
AT shahzadr comparisonofchoroidalthicknessmeasurementsbetweenspectraldomainoctandsweptsourceoctinnormalanddiseasedeyes
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