Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes
Sidra Zafar,1 MA Rehman Siddiqui,2,3 Rida Shahzad1 1Medical College, Aga Khan University Hospital, 2Department of Ophthalmology, Shahzad Eye Hospital, 3South City Hospital, Karachi, Pakistan Purpose: Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study w...
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Dove Medical Press
2016
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oai:doaj.org-article:0ff874b1120641fe89052c07384889b62021-12-02T02:59:47ZComparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes1177-5483https://doaj.org/article/0ff874b1120641fe89052c07384889b62016-11-01T00:00:00Zhttps://www.dovepress.com/comparison-of-choroidal-thickness-measurements-between-spectral-domain-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Sidra Zafar,1 MA Rehman Siddiqui,2,3 Rida Shahzad1 1Medical College, Aga Khan University Hospital, 2Department of Ophthalmology, Shahzad Eye Hospital, 3South City Hospital, Karachi, Pakistan Purpose: Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study was to compare SFCT measurements between Topcon 3D 2000 spectral-domain optical coherence tomography (SD-OCT) and Topcon swept-source OCT (SS-OCT), with different laser wavelengths, in normal and diseased populations. Materials and methods: This was a prospective, cross-sectional, noninterventional study including 27 normal volunteers and 27 participants with retinal disease. OCT scans were performed sequentially and under standardized conditions using both SD-OCT and SS-OCT. The OCT scans were evaluated by two independent graders. Paired t-tests and intraclass correlation coefficients (ICCs) were used to assess the statistically significant difference between SFCT measurements as measured by the two devices. Results: Mean SFCT measurements for all 54 participants were 264.9±103.1 µm using SD-OCT (range: 47–470 µm) and 278.5±110.5 µm using SS-OCT (range: 56–502 µm), with an inter-device ICC of 0.850. Greater variability was noted in the diseased eyes. Inter-device ICCs were 0.870 (95% CI; 0.760–0.924) and 0.840 (95% CI; 0.654–0.930) for normal and diseased eyes, respectively. However, the difference was not statistically significant (P=0.132). Conclusion: Both machines reliably measure SFCT. Larger studies are needed to confirm these findings. Keywords: choroidal imaging, diseased, normal, SD-OCT, SS-OCTZafar SSiddiqui MARShahzad RDove Medical PressarticleKeywords: Choroidal imagingdiseasednormalSD-OCTSS-OCT.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 2271-2276 (2016) |
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Keywords: Choroidal imaging diseased normal SD-OCT SS-OCT. Ophthalmology RE1-994 |
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Keywords: Choroidal imaging diseased normal SD-OCT SS-OCT. Ophthalmology RE1-994 Zafar S Siddiqui MAR Shahzad R Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes |
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Sidra Zafar,1 MA Rehman Siddiqui,2,3 Rida Shahzad1 1Medical College, Aga Khan University Hospital, 2Department of Ophthalmology, Shahzad Eye Hospital, 3South City Hospital, Karachi, Pakistan Purpose: Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study was to compare SFCT measurements between Topcon 3D 2000 spectral-domain optical coherence tomography (SD-OCT) and Topcon swept-source OCT (SS-OCT), with different laser wavelengths, in normal and diseased populations. Materials and methods: This was a prospective, cross-sectional, noninterventional study including 27 normal volunteers and 27 participants with retinal disease. OCT scans were performed sequentially and under standardized conditions using both SD-OCT and SS-OCT. The OCT scans were evaluated by two independent graders. Paired t-tests and intraclass correlation coefficients (ICCs) were used to assess the statistically significant difference between SFCT measurements as measured by the two devices. Results: Mean SFCT measurements for all 54 participants were 264.9±103.1 µm using SD-OCT (range: 47–470 µm) and 278.5±110.5 µm using SS-OCT (range: 56–502 µm), with an inter-device ICC of 0.850. Greater variability was noted in the diseased eyes. Inter-device ICCs were 0.870 (95% CI; 0.760–0.924) and 0.840 (95% CI; 0.654–0.930) for normal and diseased eyes, respectively. However, the difference was not statistically significant (P=0.132). Conclusion: Both machines reliably measure SFCT. Larger studies are needed to confirm these findings. Keywords: choroidal imaging, diseased, normal, SD-OCT, SS-OCT |
format |
article |
author |
Zafar S Siddiqui MAR Shahzad R |
author_facet |
Zafar S Siddiqui MAR Shahzad R |
author_sort |
Zafar S |
title |
Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes |
title_short |
Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes |
title_full |
Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes |
title_fullStr |
Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes |
title_full_unstemmed |
Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes |
title_sort |
comparison of choroidal thickness measurements between spectral-domain oct and swept-source oct in normal and diseased eyes |
publisher |
Dove Medical Press |
publishDate |
2016 |
url |
https://doaj.org/article/0ff874b1120641fe89052c07384889b6 |
work_keys_str_mv |
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