Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>

ABSTRACT Microbial biofilm communities are protected against environmental extremes or clearance by antimicrobial agents or the host immune response. They also serve as a site from which microbial populations search for new niches by dispersion via single planktonic cells or by detachment by protect...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nick G. Cogan, Janette M. Harro, Paul Stoodley, Mark E. Shirtliff
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2016
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/0ff9894c538c495bb6f622dae01f5cbe
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0ff9894c538c495bb6f622dae01f5cbe
record_format	dspace
spelling	oai:doaj.org-article:0ff9894c538c495bb6f622dae01f5cbe2021-11-15T15:50:17ZPredictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>10.1128/mBio.00815-162150-7511https://doaj.org/article/0ff9894c538c495bb6f622dae01f5cbe2016-07-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00815-16https://doaj.org/toc/2150-7511ABSTRACT Microbial biofilm communities are protected against environmental extremes or clearance by antimicrobial agents or the host immune response. They also serve as a site from which microbial populations search for new niches by dispersion via single planktonic cells or by detachment by protected biofilm aggregates that, until recently, were thought to become single cells ready for attachment. Mathematically modeling these events has provided investigators with testable hypotheses for further study. Such was the case in the recent article by Kragh et al. (K. N. Kragh, J. B. Hutchison, G. Melaugh, C. Rodesney, A. E. Roberts, Y. Irie, P. Ø. Jensen, S. P. Diggle, R. J. Allen, V. Gordon, and T. Bjarnsholt, mBio 7:e00237-16, 2016, http://dx.doi.org/10.1128/mBio.00237-16), in which investigators were able to identify the differential competitive advantage of biofilm aggregates to directly attach to surfaces compared to the single-celled planktonic populations. Therefore, as we delve deeper into the properties of the biofilm mode of growth, not only do we need to understand the complexity of biofilms, but we must also account for the properties of the dispersed and detached populations and their effect on reseeding.Nick G. CoganJanette M. HarroPaul StoodleyMark E. ShirtliffAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 7, Iss 3 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Nick G. Cogan Janette M. Harro Paul Stoodley Mark E. Shirtliff Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
description	ABSTRACT Microbial biofilm communities are protected against environmental extremes or clearance by antimicrobial agents or the host immune response. They also serve as a site from which microbial populations search for new niches by dispersion via single planktonic cells or by detachment by protected biofilm aggregates that, until recently, were thought to become single cells ready for attachment. Mathematically modeling these events has provided investigators with testable hypotheses for further study. Such was the case in the recent article by Kragh et al. (K. N. Kragh, J. B. Hutchison, G. Melaugh, C. Rodesney, A. E. Roberts, Y. Irie, P. Ø. Jensen, S. P. Diggle, R. J. Allen, V. Gordon, and T. Bjarnsholt, mBio 7:e00237-16, 2016, http://dx.doi.org/10.1128/mBio.00237-16), in which investigators were able to identify the differential competitive advantage of biofilm aggregates to directly attach to surfaces compared to the single-celled planktonic populations. Therefore, as we delve deeper into the properties of the biofilm mode of growth, not only do we need to understand the complexity of biofilms, but we must also account for the properties of the dispersed and detached populations and their effect on reseeding.
format	article
author	Nick G. Cogan Janette M. Harro Paul Stoodley Mark E. Shirtliff
author_facet	Nick G. Cogan Janette M. Harro Paul Stoodley Mark E. Shirtliff
author_sort	Nick G. Cogan
title	Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
title_short	Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
title_full	Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
title_fullStr	Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
title_full_unstemmed	Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
title_sort	predictive computer models for biofilm detachment properties in <named-content content-type="genus-species">pseudomonas aeruginosa</named-content>
publisher	American Society for Microbiology
publishDate	2016
url	https://doaj.org/article/0ff9894c538c495bb6f622dae01f5cbe
work_keys_str_mv	AT nickgcogan predictivecomputermodelsforbiofilmdetachmentpropertiesinnamedcontentcontenttypegenusspeciespseudomonasaeruginosanamedcontent AT janettemharro predictivecomputermodelsforbiofilmdetachmentpropertiesinnamedcontentcontenttypegenusspeciespseudomonasaeruginosanamedcontent AT paulstoodley predictivecomputermodelsforbiofilmdetachmentpropertiesinnamedcontentcontenttypegenusspeciespseudomonasaeruginosanamedcontent AT markeshirtliff predictivecomputermodelsforbiofilmdetachmentpropertiesinnamedcontentcontenttypegenusspeciespseudomonasaeruginosanamedcontent
_version_	1718427381377531904

Predictive Computer Models for Biofilm Detachment Properties in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>

Ejemplares similares