Cell-based glycan arrays for probing glycan–glycan binding protein interactions

Glycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically recognizing these tags.

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Autores principales:	Jennie Grace Briard, Hao Jiang, Kelley W. Moremen, Matthew Scott Macauley, Peng Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0ffb5181213f47b5a814ffdccd1b3795
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spelling	oai:doaj.org-article:0ffb5181213f47b5a814ffdccd1b37952021-12-02T15:34:23ZCell-based glycan arrays for probing glycan–glycan binding protein interactions10.1038/s41467-018-03245-52041-1723https://doaj.org/article/0ffb5181213f47b5a814ffdccd1b37952018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03245-5https://doaj.org/toc/2041-1723Glycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically recognizing these tags.Jennie Grace BriardHao JiangKelley W. MoremenMatthew Scott MacauleyPeng WuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jennie Grace Briard Hao Jiang Kelley W. Moremen Matthew Scott Macauley Peng Wu Cell-based glycan arrays for probing glycan–glycan binding protein interactions
description	Glycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically recognizing these tags.
format	article
author	Jennie Grace Briard Hao Jiang Kelley W. Moremen Matthew Scott Macauley Peng Wu
author_facet	Jennie Grace Briard Hao Jiang Kelley W. Moremen Matthew Scott Macauley Peng Wu
author_sort	Jennie Grace Briard
title	Cell-based glycan arrays for probing glycan–glycan binding protein interactions
title_short	Cell-based glycan arrays for probing glycan–glycan binding protein interactions
title_full	Cell-based glycan arrays for probing glycan–glycan binding protein interactions
title_fullStr	Cell-based glycan arrays for probing glycan–glycan binding protein interactions
title_full_unstemmed	Cell-based glycan arrays for probing glycan–glycan binding protein interactions
title_sort	cell-based glycan arrays for probing glycan–glycan binding protein interactions
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0ffb5181213f47b5a814ffdccd1b3795
work_keys_str_mv	AT jenniegracebriard cellbasedglycanarraysforprobingglycanglycanbindingproteininteractions AT haojiang cellbasedglycanarraysforprobingglycanglycanbindingproteininteractions AT kelleywmoremen cellbasedglycanarraysforprobingglycanglycanbindingproteininteractions AT matthewscottmacauley cellbasedglycanarraysforprobingglycanglycanbindingproteininteractions AT pengwu cellbasedglycanarraysforprobingglycanglycanbindingproteininteractions
_version_	1718386822034227200

Cell-based glycan arrays for probing glycan–glycan binding protein interactions

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