Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula

Abstract Background Mycobacterium massiliense is a rapidly growing a non-tuberculous mycobacterium that has been validated as a separate species from the Mycobacterium abscessus group. Only few antibiotics have demonstrated germicidal activity against Mycobacterium massiliense, and some of those inc...

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Autores principales: Haroon Nawaz, Ayesha A. Choudhry, William Morse
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Publicado: SpringerOpen 2021
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spelling oai:doaj.org-article:0fff6077222746cab7bf0a1d3254aa632021-12-05T12:03:30ZCase report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula10.1186/s43162-021-00069-61110-77822090-9098https://doaj.org/article/0fff6077222746cab7bf0a1d3254aa632021-12-01T00:00:00Zhttps://doi.org/10.1186/s43162-021-00069-6https://doaj.org/toc/1110-7782https://doaj.org/toc/2090-9098Abstract Background Mycobacterium massiliense is a rapidly growing a non-tuberculous mycobacterium that has been validated as a separate species from the Mycobacterium abscessus group. Only few antibiotics have demonstrated germicidal activity against Mycobacterium massiliense, and some of those include amikacin, clarithromycin, and cefoxitin. Case presentation We present the first reported case of near-fatal septic shock caused by disseminated Mycobacterium massiliense after de-clotting of an infected arteriovenous fistula, in a patient with end-stage renal disease with concomitant human immunodeficiency virus infection. Early recognition of the culprit organism and treatment with a combination therapy of clarithromycin and amikacin led to rapid improvement. Conclusion This unique case can highlight the importance of taking into consideration Mycobacterium massiliense infection as a cause of arteriovenous fistula thrombosis and highlights the risk of disseminated infection leading to life threatening sepsis upon de-clotting of the fistula.Haroon NawazAyesha A. ChoudhryWilliam MorseSpringerOpenarticleMycobacterium massilienseArteriovenous fistulaDe-clotting arteriovenous fistulaSepsisInternal medicineRC31-1245ENThe Egyptian Journal of Internal Medicine, Vol 33, Iss 1, Pp 1-3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Mycobacterium massiliense
Arteriovenous fistula
De-clotting arteriovenous fistula
Sepsis
Internal medicine
RC31-1245
spellingShingle Mycobacterium massiliense
Arteriovenous fistula
De-clotting arteriovenous fistula
Sepsis
Internal medicine
RC31-1245
Haroon Nawaz
Ayesha A. Choudhry
William Morse
Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
description Abstract Background Mycobacterium massiliense is a rapidly growing a non-tuberculous mycobacterium that has been validated as a separate species from the Mycobacterium abscessus group. Only few antibiotics have demonstrated germicidal activity against Mycobacterium massiliense, and some of those include amikacin, clarithromycin, and cefoxitin. Case presentation We present the first reported case of near-fatal septic shock caused by disseminated Mycobacterium massiliense after de-clotting of an infected arteriovenous fistula, in a patient with end-stage renal disease with concomitant human immunodeficiency virus infection. Early recognition of the culprit organism and treatment with a combination therapy of clarithromycin and amikacin led to rapid improvement. Conclusion This unique case can highlight the importance of taking into consideration Mycobacterium massiliense infection as a cause of arteriovenous fistula thrombosis and highlights the risk of disseminated infection leading to life threatening sepsis upon de-clotting of the fistula.
format article
author Haroon Nawaz
Ayesha A. Choudhry
William Morse
author_facet Haroon Nawaz
Ayesha A. Choudhry
William Morse
author_sort Haroon Nawaz
title Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
title_short Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
title_full Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
title_fullStr Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
title_full_unstemmed Case report of a near-fatal case of Mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
title_sort case report of a near-fatal case of mycobacterium massiliense sepsis after de-clotting of an arteriovenous fistula
publisher SpringerOpen
publishDate 2021
url https://doaj.org/article/0fff6077222746cab7bf0a1d3254aa63
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