Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.

Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.

Amyloid precursor protein (APP) is a transmembrane glycoprotein frequently studied for its role in Alzheimer's disease. Our recent study in APP knockout (KO) mice identified an important role for APP in modulating normal neuronal development in the retina. However the role APP plays in the adul...

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Autores principales: Tracy Ho, Kirstan A Vessey, Roberto Cappai, Virginie Dinet, Frédéric Mascarelli, Giuseppe D Ciccotosto, Erica L Fletcher
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/10002006621145f0a3275bafc4d891b7
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