Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

Crosstalk between protein oxidation and other post-translational modifications remains unexplored. Here, the authors map the phosphoproteome, cysteine redox proteome and total proteome of adipocytes under acute oxidative stress and reveal crosstalk between cysteine oxidation and phosphorylation-base...

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Autores principales:	Zhiduan Su, James G. Burchfield, Pengyi Yang, Sean J. Humphrey, Guang Yang, Deanne Francis, Sabina Yasmin, Sung-Young Shin, Dougall M. Norris, Alison L. Kearney, Miro A. Astore, Jonathan Scavuzzo, Kelsey H. Fisher-Wellman, Qiao-Ping Wang, Benjamin L. Parker, G. Gregory Neely, Fatemeh Vafaee, Joyce Chiu, Reichelle Yeo, Philip J. Hogg, Daniel J. Fazakerley, Lan K. Nguyen, Serdar Kuyucak, David E. James
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/100de65dcd654d9fbe6eaea348b3c57b
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spelling	oai:doaj.org-article:100de65dcd654d9fbe6eaea348b3c57b2021-12-02T17:32:40ZGlobal redox proteome and phosphoproteome analysis reveals redox switch in Akt10.1038/s41467-019-13114-42041-1723https://doaj.org/article/100de65dcd654d9fbe6eaea348b3c57b2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13114-4https://doaj.org/toc/2041-1723Crosstalk between protein oxidation and other post-translational modifications remains unexplored. Here, the authors map the phosphoproteome, cysteine redox proteome and total proteome of adipocytes under acute oxidative stress and reveal crosstalk between cysteine oxidation and phosphorylation-based signalling.Zhiduan SuJames G. BurchfieldPengyi YangSean J. HumphreyGuang YangDeanne FrancisSabina YasminSung-Young ShinDougall M. NorrisAlison L. KearneyMiro A. AstoreJonathan ScavuzzoKelsey H. Fisher-WellmanQiao-Ping WangBenjamin L. ParkerG. Gregory NeelyFatemeh VafaeeJoyce ChiuReichelle YeoPhilip J. HoggDaniel J. FazakerleyLan K. NguyenSerdar KuyucakDavid E. JamesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhiduan Su James G. Burchfield Pengyi Yang Sean J. Humphrey Guang Yang Deanne Francis Sabina Yasmin Sung-Young Shin Dougall M. Norris Alison L. Kearney Miro A. Astore Jonathan Scavuzzo Kelsey H. Fisher-Wellman Qiao-Ping Wang Benjamin L. Parker G. Gregory Neely Fatemeh Vafaee Joyce Chiu Reichelle Yeo Philip J. Hogg Daniel J. Fazakerley Lan K. Nguyen Serdar Kuyucak David E. James Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
description	Crosstalk between protein oxidation and other post-translational modifications remains unexplored. Here, the authors map the phosphoproteome, cysteine redox proteome and total proteome of adipocytes under acute oxidative stress and reveal crosstalk between cysteine oxidation and phosphorylation-based signalling.
format	article
author	Zhiduan Su James G. Burchfield Pengyi Yang Sean J. Humphrey Guang Yang Deanne Francis Sabina Yasmin Sung-Young Shin Dougall M. Norris Alison L. Kearney Miro A. Astore Jonathan Scavuzzo Kelsey H. Fisher-Wellman Qiao-Ping Wang Benjamin L. Parker G. Gregory Neely Fatemeh Vafaee Joyce Chiu Reichelle Yeo Philip J. Hogg Daniel J. Fazakerley Lan K. Nguyen Serdar Kuyucak David E. James
author_facet	Zhiduan Su James G. Burchfield Pengyi Yang Sean J. Humphrey Guang Yang Deanne Francis Sabina Yasmin Sung-Young Shin Dougall M. Norris Alison L. Kearney Miro A. Astore Jonathan Scavuzzo Kelsey H. Fisher-Wellman Qiao-Ping Wang Benjamin L. Parker G. Gregory Neely Fatemeh Vafaee Joyce Chiu Reichelle Yeo Philip J. Hogg Daniel J. Fazakerley Lan K. Nguyen Serdar Kuyucak David E. James
author_sort	Zhiduan Su
title	Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
title_short	Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
title_full	Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
title_fullStr	Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
title_full_unstemmed	Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
title_sort	global redox proteome and phosphoproteome analysis reveals redox switch in akt
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/100de65dcd654d9fbe6eaea348b3c57b
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Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

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