Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function

3D bioprinting of skeletal muscle using primary human muscle progenitor cells results in correct muscle architecture, but functional restoration in rodent models is limited. Here the authors include human neural stem cells into bioprinted skeletal muscle and observe improved architecture and functio...

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Autores principales: Ji Hyun Kim, Ickhee Kim, Young-Joon Seol, In Kap Ko, James J. Yoo, Anthony Atala, Sang Jin Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/100df44b6f774e4298073a310e431d95
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spelling oai:doaj.org-article:100df44b6f774e4298073a310e431d952021-12-02T10:59:14ZNeural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function10.1038/s41467-020-14930-92041-1723https://doaj.org/article/100df44b6f774e4298073a310e431d952020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14930-9https://doaj.org/toc/2041-17233D bioprinting of skeletal muscle using primary human muscle progenitor cells results in correct muscle architecture, but functional restoration in rodent models is limited. Here the authors include human neural stem cells into bioprinted skeletal muscle and observe improved architecture and function in vivo.Ji Hyun KimIckhee KimYoung-Joon SeolIn Kap KoJames J. YooAnthony AtalaSang Jin LeeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ji Hyun Kim
Ickhee Kim
Young-Joon Seol
In Kap Ko
James J. Yoo
Anthony Atala
Sang Jin Lee
Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
description 3D bioprinting of skeletal muscle using primary human muscle progenitor cells results in correct muscle architecture, but functional restoration in rodent models is limited. Here the authors include human neural stem cells into bioprinted skeletal muscle and observe improved architecture and function in vivo.
format article
author Ji Hyun Kim
Ickhee Kim
Young-Joon Seol
In Kap Ko
James J. Yoo
Anthony Atala
Sang Jin Lee
author_facet Ji Hyun Kim
Ickhee Kim
Young-Joon Seol
In Kap Ko
James J. Yoo
Anthony Atala
Sang Jin Lee
author_sort Ji Hyun Kim
title Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
title_short Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
title_full Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
title_fullStr Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
title_full_unstemmed Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
title_sort neural cell integration into 3d bioprinted skeletal muscle constructs accelerates restoration of muscle function
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/100df44b6f774e4298073a310e431d95
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