The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway

The yeast Hsp70 homolog Ssb is a chaperone that binds translating ribosomes where it is thought to function primarily by promoting nascent peptide folding. Here the authors find that the ribosome biogenesis defect associated with the loss of Ssb is attributable to a specific disruption in TORC1 sign...

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Autores principales:	Kaivalya Mudholkar, Edith Fitzke, Claudia Prinz, Matthias P. Mayer, Sabine Rospert
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1014f8b7393e4116a44d4ead6d78f46e
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spelling	oai:doaj.org-article:1014f8b7393e4116a44d4ead6d78f46e2021-12-02T17:01:22ZThe Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway10.1038/s41467-017-00635-z2041-1723https://doaj.org/article/1014f8b7393e4116a44d4ead6d78f46e2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00635-zhttps://doaj.org/toc/2041-1723The yeast Hsp70 homolog Ssb is a chaperone that binds translating ribosomes where it is thought to function primarily by promoting nascent peptide folding. Here the authors find that the ribosome biogenesis defect associated with the loss of Ssb is attributable to a specific disruption in TORC1 signaling rather than defects in ribosomal protein folding.Kaivalya MudholkarEdith FitzkeClaudia PrinzMatthias P. MayerSabine RospertNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kaivalya Mudholkar Edith Fitzke Claudia Prinz Matthias P. Mayer Sabine Rospert The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
description	The yeast Hsp70 homolog Ssb is a chaperone that binds translating ribosomes where it is thought to function primarily by promoting nascent peptide folding. Here the authors find that the ribosome biogenesis defect associated with the loss of Ssb is attributable to a specific disruption in TORC1 signaling rather than defects in ribosomal protein folding.
format	article
author	Kaivalya Mudholkar Edith Fitzke Claudia Prinz Matthias P. Mayer Sabine Rospert
author_facet	Kaivalya Mudholkar Edith Fitzke Claudia Prinz Matthias P. Mayer Sabine Rospert
author_sort	Kaivalya Mudholkar
title	The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
title_short	The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
title_full	The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
title_fullStr	The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
title_full_unstemmed	The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
title_sort	hsp70 homolog ssb affects ribosome biogenesis via the torc1-sch9 signaling pathway
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1014f8b7393e4116a44d4ead6d78f46e
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The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway

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